Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns

DEW Chatterton, DN Nguyen, SB Bering… - The international journal …, 2013 - Elsevier
The human newborn infant is susceptible to gut inflammatory disorders. In particular, growth-
restricted infants or infants born prematurely may develop a severe form of intestinal …

Bioactive peptides derived from human milk proteins—mechanisms of action

Y Wada, B Lönnerdal - The Journal of nutritional biochemistry, 2014 - Elsevier
Human milk contains a multitude of bioactive proteins with very diverse functions, which are
beneficial for the rapidly growing neonate. The large variety of bioactivities is accomplished …

Glycomacropeptide is a prebiotic that reduces Desulfovibrio bacteria, increases cecal short-chain fatty acids, and is anti-inflammatory in mice

EA Sawin, TJ De Wolfe, B Aktas… - American Journal …, 2015 - journals.physiology.org
Glycomacropeptide (GMP) is a 64-amino acid (AA) glycophosphopeptide with application to
the nutritional management of phenylketonuria (PKU), obesity, and inflammatory bowel …

[HTML][HTML] Health-related aspects of milk proteins

SH Davoodi, R Shahbazi, S Esmaeili… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Milk is an important component of a balanced diet and contains numerous valuable
constituents. Considerable acclaimed health benefits of milk are related to its proteins, not …

Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID)

K Watashi, G Liang, M Iwamoto, H Marusawa… - Journal of Biological …, 2013 - ASBMB
Virus infection is restricted by intracellular immune responses in host cells, and this is
typically modulated by stimulation of cytokines. The cytokines and host factors that …

Hydrolysed formulas in the management of cow's milk allergy: new insights, pitfalls and tips

E D'Auria, S Salvatore, M Acunzo, D Peroni… - Nutrients, 2021 - mdpi.com
An allergy to cow's milk requires the avoidance of cow's milk proteins and, in some infants,
the use of a hypoallergenic formula. This review aims to summarize the current evidence …

Cow's milk allergy: immunomodulation by dietary intervention

E D'Auria, S Salvatore, E Pozzi, C Mantegazza… - Nutrients, 2019 - mdpi.com
Cow's milk proteins cause allergic symptoms in 2% to 3% of all infants. In these individuals,
the physiological mechanism of tolerance is broken with subsequent possible sensitization …

Glycomacropeptide bioactivity and health: a review highlighting action mechanisms and signaling pathways

LE Córdova-Dávalos, M Jiménez, E Salinas - Nutrients, 2019 - mdpi.com
Food-derived bioactive peptides are reported as beneficial and safe for human health.
Glycomacropeptide (GMP) is a milk-protein-derived peptide that, in addition to its nutritional …

Food derived bioactive peptides and intestinal barrier function

O Martínez-Augustin, B Rivero-Gutiérrez… - International Journal of …, 2014 - mdpi.com
A wide range of food-derived bioactive peptides have been shown to exert health-promoting
actions and are therefore considered functional foods or nutraceuticals. Some of these …

Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR 4

F Capitán‐Cañadas… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Prebiotic oligosaccharides are currently used in a variety of clinical settings for their
effects on intestinal microbiota. Here, we have examined the direct, microbiota independent …