More than a quarter of the world's population is at risk of infection with the soil-transmitted
helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator …

The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its
mechanism still remains with relevant controversies. Some studies defend that early …

Background Vaccine immunogenicity and effectiveness vary geographically. Chronic
immunomodulating parasitic infections including schistosomes and malaria have been …

Background There is considerable research interest in the role of helminth infections in the
development of allergic diseases. However, findings from previous studies are mixed …

There is much debate about the interaction between helminths and allergic disease. The
“Hygiene Hypothesis,” a very popular concept among scientists and the lay public, states …

Parasitic helminths must establish chronic infections to complete their life cycle and
therefore are potent modulators of multiple facets of host physiology. Parasitic helminths …

Abstract Purpose of Review Helminth infections modify the natural history of allergic
diseases, by either decreasing or increasing their symptoms. Several helminth components …

Several vaccines elicit lower efficacy or impaired immune responses in rural compared to
urban settings, and in tropical low-income countries compared to high-income countries. An …

The dynamically growing incidence of food allergies forces the scientific community to
develop new methods for their diagnosis, differentiation, and effective treatment. Parasitoses …

Background The prevalence of allergy-related diseases is increasing in low-income
countries. Parasitic helminths, common in these settings, may be protective. We …