Expression of the sodium iodide symporter (NIS) is required for efficient iodide uptake in
thyroid and lactating breast. Since most differentiated thyroid cancer expresses NIS, β …

Molecular imaging includes proteomic, metabolic, cellular biologic process, and genetic
imaging. In a narrow sense, molecular imaging means genetic imaging and can be called …

Background Expression and function of sodium iodide symporter (NIS) is requisite for
efficient iodide transport in thyrocytes, and its presence in cancer cells allows the use of …

Biotherapies involve the utilization of antibodies, genetically modified viruses, bacteria or
cells for therapeutic purposes. Molecular imaging has the potential to provide unique …

The sodium iodide symporter (SLC5A5/NIS) as theranostic gene would allow for non-
invasive imaging of functional NIS expression and therapeutic radioiodine application …

The combination of nanotechnology with molecular imaging has great potential for the
development of diagnostics and therapeutics, and multimodal imaging enables versatile …

Since the specific accumulation of iodide in thyroid was found in 1915, radioiodine has been
widely applied to diagnose and treat thyroid cancer. Iodide uptake occurs across the …

Purpose: Oncolytic adenoviruses are promising tools for cancer therapy. Although several
clinical reports have indicated both safety and promising antitumor capabilities for these …

Purpose In vivo imaging of the spread of oncolytic viruses using the Na/I symporter (NIS) has
been proposed. Here, we assessed whether the presence of NIS in the viral genome affects …

In clinical practices, the therapeutic outcomes and prognosis of hepatocellular carcinoma
(HCC) patients with different tumor numbers after surgery are very different; however, the …