This review focuses on imaging DNA and single RNA molecules in living cells to define
eukaryotic functional organization and dynamic processes. The latest advances in …

Nucleic acids, aside from being best known as the carrier of genetic information, are
versatile biomaterials for constructing nanoscopic devices for biointerfacing, owing to their …

Strand displacement reactions are widely used in DNA nanotechnology as a building block
for engineering molecular computers and machines. Here, we demonstrate that strand …

Live-cell imaging has provided the life sciences with insights into the cell biology and
dynamics. Fluorescent labeling of target molecules proves to be indispensable in this …

New techniques for single‐cell analysis enable new discoveries in gene expression and
systems biology. Time‐dependent measurements on individual cells are necessary, yet the …

Single‐cell explorations offer a unique window to inspect molecules and events relevant to
mechanisms and heterogeneity constituting the central dogma of biology. A large number of …

Fluorogenic oligonucleotide probes facilitate the detection and localization of RNA targets
within cells. However, quantitative measurements of mRNA abundance are difficult when …

The ability to detect and visualize nucleic acids in living organisms is crucial for under-
standing cellular processes. For this purpose, the research group of Prof. Dr. Oliver Seitz has …