T1 mapping, T2 mapping and MR elastography of the liver for detection and staging of liver fibrosis

DH Hoffman, A Ayoola, D Nickel, F Han… - Abdominal …, 2020 - Springer
Purpose To compare liver stiffness measurements obtained from MR elastography with liver
T1 relaxation times obtained from T1 mapping and T2 relaxation times obtained from T2 …

Non-invasive assessment of liver fibrosis in autoimmune hepatitis: Diagnostic value of liver magnetic resonance parametric mapping including extracellular volume …

N Mesropyan, P Kupczyk, L Dold, TJ Weismüller… - Abdominal …, 2021 - Springer
Purpose Autoimmune hepatitis (AIH) is an immune-mediated chronic liver disease that leads
to severe fibrosis and cirrhosis. The aim of this study was to determine the diagnostic value …

Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation

MJ Lyall, JP Thomson, J Cartier, R Ottaviano… - Epigenetics, 2020 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) is now the commonest cause of liver disease in
developed countries affecting 25–33% of the general population and up to 75% of those …

Magnetic resonance parametric mapping of the spleen for non-invasive assessment of portal hypertension

N Mesropyan, A Isaak, A Faron, M Praktiknjo… - European …, 2021 - Springer
Objectives In patients with advanced liver disease, portal hypertension is an important risk
factor, leading to complications such as esophageal variceal bleeding, ascites, and hepatic …

Diagnostic value of magnetic resonance parametric mapping for non-invasive assessment of liver fibrosis in patients with primary sclerosing cholangitis

N Mesropyan, P Kupczyk, GM Kukuk, L Dold… - BMC Medical …, 2021 - Springer
Background Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease,
characterized by bile duct inflammation and destruction, leading to biliary fibrosis and …

In Vivo Magnetic Resonance Spectroscopy of Hyperpolarized [1‐13C]Pyruvate and Proton Density Fat Fraction in a Guinea Pig Model of Non‐Alcoholic Fatty Liver …

LM Smith, CB Pitts, LJ Friesen‐Waldner… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Alterations in glycolysis are central to the increasing incidence of non‐alcoholic
fatty liver disease (NAFLD), highlighting a need for in vivo, non‐invasive technologies to …

Non-invasive photothermal strain imaging of non-alcoholic fatty liver disease in live animals

C Choi, W Choi, J Kim, C Kim - IEEE Transactions on Medical …, 2021 - ieeexplore.ieee.org
The prevalence of non-alcoholic fatty liver diseases (NAFLD) has increased steadily over
the past decade. Thus, diagnosing NAFLD at the earliest stage, which is a reversible …

Biased Quantification of Rat Liver Fibrosis—Meta-Analysis with Practical Recommendations and Clinical Implications

P Mik, K Barannikava, P Surkova - Journal of Clinical Medicine, 2023 - mdpi.com
For liver fibrosis assessment, the liver biopsy is usually stained with Masson's trichrome (MT)
or picrosirius red (PSR) to quantify liver connective tissue (LCT) for fibrosis scoring …

Prospective comparison of longitudinal change in hepatic proton density fat fraction (PDFF) estimated by magnitude-based MRI (MRI-M) and complex-based MRI (MRI …

A Mamidipalli, KJ Fowler, G Hamilton, T Wolfson… - European …, 2020 - Springer
Purpose To compare longitudinal hepatic proton density fat fraction (PDFF) changes
estimated by magnitude-vs. complex-based chemical-shift-encoded MRI during a weight …

Rapid and Reliable Steatosis Rat Model Shrsp5-Dmcr for Cold Storage Experiment

M Fukai, H Sugimori, S Sakamoto, K Shibata… - Transplantation …, 2023 - Elsevier
Interventions for liver grafts with moderate macrovesicular steatosis have been important in
enlarging donor pools. Here, we tested a high-fat and cholesterol (HFC) diet to create a …