Nutritional immunity: the battle for nutrient metals at the host–pathogen interface

CC Murdoch, EP Skaar - Nature Reviews Microbiology, 2022 - nature.com
Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

Calprotectin: from biomarker to biological function

A Jukic, L Bakiri, EF Wagner, H Tilg, TE Adolph - Gut, 2021 - gut.bmj.com
The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …

Clinical implications of preterm infant gut microbiome development

DB Healy, CA Ryan, RP Ross, C Stanton… - Nature …, 2022 - nature.com
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

[HTML][HTML] Gut microbiota dysbiosis, oxidative stress, inflammation, and epigenetic alterations in metabolic diseases

H Mostafavi Abdolmaleky, JR Zhou - Antioxidants, 2024 - mdpi.com
Gut dysbiosis, resulting from an imbalance in the gut microbiome, can induce excessive
production of reactive oxygen species (ROS), leading to inflammation, DNA damage …

S100A8 and S100A9 in Cancer

Y Chen, Y Ouyang, Z Li, X Wang, J Ma - Biochimica et Biophysica Acta …, 2023 - Elsevier
Abstract S100A8 and S100A9 are Ca 2+ binding proteins that belong to the S100 family.
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …

Modulation of bone remodeling by the gut microbiota: a new therapy for osteoporosis

Z Lyu, Y Hu, Y Guo, D Liu - Bone research, 2023 - nature.com
The gut microbiota (GM) plays a crucial role in maintaining the overall health and well-being
of the host. Recent studies have demonstrated that the GM may significantly influence bone …

Protective role of spermidine in colitis and colon carcinogenesis

AP Gobert, YL Latour, M Asim, DP Barry, MM Allaman… - Gastroenterology, 2022 - Elsevier
Background & Aims Because inflammatory bowel disease is increasing worldwide and can
lead to colitis-associated carcinoma (CAC), new interventions are needed. We have shown …

m6A modification-tuned sphingolipid metabolism regulates postnatal liver development in male mice

S Wang, S Chen, J Sun, P Han, B Xu, X Li, Y Zhong… - Nature …, 2023 - nature.com
Different organs undergo distinct transcriptional, epigenetic and physiological alterations
that guarantee their functional maturation after birth. However, the roles of epitranscriptomic …

The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two …

M Kaczmarczyk, U Löber, K Adamek… - Journal of translational …, 2021 - Springer
Background The intestinal barrier plays an important role in the defense against infections,
and nutritional, endocrine, and immune functions. The gut microbiota playing an important …

[HTML][HTML] The monkeypox virus-host interplays

XM Yi, YL Lei, M Li, Z Li, S Li - Cell Insight, 2024 - Elsevier
Monkeypox virus (MPXV) is a DNA virus belonging to the Orthopoxvirus genus within the
Poxviridae family which can cause a zoonotic infection. The unexpected non-endemic …