Quality over quantity: powering neuroimaging samples in psychiatry

C Makowski, TE Nichols, AM Dale - Neuropsychopharmacology, 2024 - nature.com
Neuroimaging has been widely adopted in psychiatric research, with hopes that these non-
invasive methods will provide important clues to the underpinnings and prediction of various …

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

N Borbye-Lorenzen, Z Zhu, E Agerbo, C Albiñana… - Cell genomics, 2023 - cell.com
Complement components have been linked to schizophrenia and autoimmune disorders.
We examined the association between neonatal circulating C3 and C4 protein …

[HTML][HTML] Dissecting the impact of complement component 4A in bipolar disorder

E Hörbeck, L Jonsson, S Malwade, R Karlsson… - Brain, Behavior, and …, 2024 - Elsevier
The genetic overlap between schizophrenia (SZ) and bipolar disorder (BD) is substantial.
Polygenic risk scores have been shown to dissect different symptom dimensions within and …

Attention-mediated genetic influences on psychotic symptomatology in adolescence

SE Chang, DE Hughes, J Zhu, M Hyat, SD Salone… - Nature Mental …, 2024 - nature.com
Attention problems are among the earliest precursors of schizophrenia. In this longitudinal
cohort study, we examine relationships between cognitive and neuropsychiatric polygenic …

Association of elevated levels of peripheral complement components with cortical thinning and impaired logical memory in drug-naïve patients with first-episode …

H Yu, P Ni, Y Tian, L Zhao, M Li, X Li, W Wei, J Wei… - Schizophrenia, 2023 - nature.com
Schizophrenia has been linked to polymorphism in genes encoding components of the
complement system, and hyperactive complement activity has been linked to immune …

Mapping the genetic and phenotypic landscape of neonatal C3 and C4 protein concentrations

LM Hernandez - Cell Genomics, 2023 - cell.com
The complement system is crucial for innate immunity and has been linked to autoimmune
and psychiatric disorders. Borbye-Lorenzen et al. 1 perform GWASs and PheWASs of …