Background: Steroid resistant nephrotic syndrome (SRNS) is a rare condition, accounting for
10–15% of all children with idiopathic nephrotic syndrome. SRNS can be caused by genetic …

Abstract Kidney Disease: Improving Global Outcomes (KDIGO) recently published the
clinical practice guideline on glomerulonephritis (GN) to assist the practitioner caring for …

We investigated the value of genetic, histopathologic, and early treatment response
information in prognosing long-term renal outcome in children with primary steroid-resistant …

This NIH-funded multicenter randomized study of focal segmental glomerulosclerosis
(FSGS) treatment compared the efficacy of a 12-month course of cyclosporine to a …

Long-term outcome of idiopathic steroid-resistant nephrotic syndrome was retrospectively
studied in 78 children in eight centers for the past 20 years. Median age at onset was 4.4 …

In rodents, parietal epithelial cells (PECs) migrating onto the glomerular tuft participate in the
formation of focal segmental glomerulosclerosis (FSGS) lesions. We investigated whether …

INTRODUTION: Steroid resistant idiopathic nephrotic syndrome (SRINS) in children is one
of the leading causes of progression to chronic kidney disease stage V (CKD V)/end stage …

First line immunosuppressive treatment in steroid-resistant nephrotic syndrome in children is
still open to discussion. We conducted a controlled multicentre randomized open label trial …

Background Recent reports from small studies in West Africa suggest that Black children
may have high rate of steroid sensitivity nephrotic syndrome (SSNS) contrary to long held …

Oxidative stress, inflammation, and fibrosis are involved in the development and progression
of focal segmental glomerulosclerosis (FSGS), a common form of idiopathic nephrotic …