The mechanism for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection requires the binding of the virus to the angiotensin-converting enzyme 2 (ACE2) …

The development and pathogenesis of atherosclerosis are significantly influenced by
lifestyle, particularly nutrition. The modern level of science and technology development …

The importance of host genetics and demography in coronavirus disease 2019 (COVID-19)
is a crucial aspect of infection, prognosis and associated case fatality rate. Individual genetic …

Little is known about the genetic determinants of medication use in preventing
cardiometabolic diseases. Using the Finnish nationwide drug purchase registry with follow …

Hypertension is one of the strongest modifiable cardiovascular risk factors, affecting an
increasing number of people worldwide. Apart from poor medication adherence, the low …

Genetic variants among individuals have been associated with ineffective control of
hypertension. Previous work has shown that hypertension has a polygenic nature, and …

Purpose: This study was performed to investigate the effects of common polymorphisms in
CYP2D6 and CYP3A5 on the plasma concentrations and antihypertensive effects of …

Background The implementation of genotyping for anti-hypertensive drugs in clinical
practice remains a challenge. We conducted this study to analyze the distribution of …

Hypertension (HTN) is a persistent public health problem affecting approximately 1.3 billion
individuals globally. Treatment-resistant hypertension (TRH) is defined as high blood …

Hypertension remains a significant health burden worldwide, re-emphasizing the
outstanding need for more effective and safer antihypertensive therapeutic approaches …