Antibiotic resistance and persistence—Implications for human health and treatment perspectives

M Huemer, S Mairpady Shambat, SD Brugger… - EMBO …, 2020 - embopress.org
Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

[HTML][HTML] Surveillance of antimicrobial resistance in low-and middle-income countries: a scattered picture

K Iskandar, L Molinier, S Hallit, M Sartelli… - … Resistance & Infection …, 2021 - Springer
Data on comprehensive population-based surveillance of antimicrobial resistance is lacking.
In low-and middle-income countries, the challenges are high due to weak laboratory …

Antibiotic resistance genes in bacteria: Occurrence, spread, and control

Z Jian, L Zeng, T Xu, S Sun, S Yan… - Journal of basic …, 2021 - Wiley Online Library
The production and use of antibiotics are becoming increasingly common worldwide, and
the problem of antibiotic resistance is increasing alarmingly. Drug‐resistant infections …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

[HTML][HTML] Terpene derivatives as a potential agent against antimicrobial resistance (AMR) pathogens

NA Mahizan, SK Yang, CL Moo, AAL Song, CM Chong… - Molecules, 2019 - mdpi.com
The evolution of antimicrobial resistance (AMR) in pathogens has prompted extensive
research to find alternative therapeutics. Plants rich with natural secondary metabolites are …

Molecular mechanisms of antibiotic resistance

JMA Blair, MA Webber, AJ Baylay, DO Ogbolu… - Nature reviews …, 2015 - nature.com
Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly
common and are causing a global health crisis. Antibiotic resistance is encoded by several …

Breakthroughs in bacterial resistance mechanisms and the potential ways to combat them

B Khameneh, R Diab, K Ghazvini, BSF Bazzaz - Microbial pathogenesis, 2016 - Elsevier
Multidrug-resistant (MDR) bacteria have increased at an alarming rate over recent decades
and cause serious problems. The emergence of resistant infections caused by these …

[HTML][HTML] Treatment options for K. pneumoniae, P. aeruginosa and A. baumannii co-resistant to carbapenems, aminoglycosides, polymyxins and tigecycline: an …

S Karakonstantis, EI Kritsotakis, A Gikas - Infection, 2020 - Springer
The management of carbapenem-resistant infections is often based on polymyxins,
tigecycline, aminoglycosides and their combinations. However, in a recent systematic …

Antibiotic resistance in the environment: a critical insight on its occurrence, fate, and eco-toxicity

S Bombaywala, A Mandpe, S Paliya… - Environmental Science and …, 2021 - Springer
The overuse, misuse, and underuse of antibiotics tend to increase the antibiotic burden in
the environment resulting into the evolution in microbial community to possess resistance …

[HTML][HTML] OXA-48-like carbapenemases producing Enterobacteriaceae in different niches

A Mairi, A Pantel, A Sotto, JP Lavigne… - European Journal of …, 2018 - Springer
The emergence of carbapenem-resistant enterobacterial species poses a serious threat to
public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are …