Trying to solve the puzzle of the interaction of ascorbic acid and iron: Redox, chelation and therapeutic implications

GJ Kontoghiorghes, A Kolnagou, CN Kontoghiorghe… - Medicines, 2020 - mdpi.com
Iron and ascorbic acid (vitamin C) are essential nutrients for the normal growth and
development of humans, and their deficiency can result in serious diseases. Their …

Mechanistic insights of chelator complexes with essential transition metals: antioxidant/pro-oxidant activity and applications in medicine

VA Timoshnikov, OY Selyutina, NE Polyakov… - International Journal of …, 2022 - mdpi.com
The antioxidant/pro-oxidant activity of drugs and dietary molecules and their role in the
maintenance of redox homeostasis, as well as the implications in health and different …

Redox interactions of vitamin C and iron: Inhibition of the pro-oxidant activity by deferiprone

VA Timoshnikov, TV Kobzeva, NE Polyakov… - International journal of …, 2020 - mdpi.com
Ascorbic acid (AscH2) is one of the most important vitamins found in the human diet, with
many biological functions including antioxidant, chelating, and coenzyme activities. Ascorbic …

[图书][B] Superoxide Ion: Volume II (1991): Chemistry and Biological Implications

IB Afanas' ev - 2017 - taylorfrancis.com
The chemical properties of superoxide ion, its biological role, and the role of other oxygen
radicals which arise as a result of its transformations are contained in this text. In Volume I …

Reactions of L-ascorbic acid with transition metal complexes

MB Davies - Polyhedron, 1992 - Elsevier
L-Ascorbic acid is found nat~ ally in a wide variety of plants and animals.'It is essential to
man, though its biochemical role is not completely understood. It is not produced by the …

Chemistry of L-ascorbic acid related to foods

ML Liao, PA Seib - Food Chemistry, 1988 - Elsevier
Chemistry of L-ascorbic Acid Related to Foods Page 1 Food Chemistry 30 (1988) 289-312
Chemistry of L-ascorbic Acid Related to Foods Ming-Long Liao & Paul A. Seib* (Received 18 …

[图书][B] Natural antioxidants: Applications in foods of animal origin

R Banerjee, AK Verma, MW Siddiqui - 2017 - books.google.com
In the recent years, considerable research has been carried out evaluating natural
substances as antioxidative additives in food products, leading to novel combinations of …

[图书][B] Reactive oxygen metabolites: chemistry and medical consequences

MK Eberhardt - 2000 - taylorfrancis.com
In recent years, the field of radical chemistry has undergone explosive growth. Although its
roots lie in organic chemistry, the implications of its findings are having enormous impact in …

Redox properties and activity of iron–citrate complexes: evidence for redox cycling

FI Adam, PL Bounds, R Kissner… - Chemical research in …, 2015 - ACS Publications
Iron in iron overload disease is present as non-transferrin-bound iron, consisting of iron,
citrate, and albumin. We investigated the redox properties of iron citrate by electrochemistry …

Electronic and structural effects of inner sphere coordination of chloride to a homoleptic copper (II) diimine complex

V Leandri, Q Daniel, H Chen, L Sun… - Inorganic …, 2018 - ACS Publications
The reaction of CuCl2 with 2, 9-dimethyl-1, 10-phenanthroline (dmp) does not lead to the
formation of [Cu (dmp) 2](Cl) 2 but instead to [Cu (dmp) 2Cl] Cl, a 5-coordinated complex, in …