Glycoproteomics

I Bagdonaite, SA Malaker, DA Polasky… - Nature Reviews …, 2022 - nature.com
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Glycosylation in health and disease

C Reily, TJ Stewart, MB Renfrow, J Novak - Nature Reviews Nephrology, 2019 - nature.com
The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

The MetaCyc database of metabolic pathways and enzymes-a 2019 update

R Caspi, R Billington, IM Keseler, A Kothari… - Nucleic acids …, 2020 - academic.oup.com
MetaCyc (MetaCyc. org) is a comprehensive reference database of metabolic pathways and
enzymes from all domains of life. It contains 2749 pathways derived from more than 60 000 …

Deducing the N-and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2

A Shajahan, NT Supekar, AS Gleinich, P Azadi - Glycobiology, 2020 - academic.oup.com
The current emergence of the novel coronavirus pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) demands the development of new …

A useful guide to lectin binding: machine-learning directed annotation of 57 unique lectin specificities

D Bojar, L Meche, G Meng, W Eng, DF Smith… - ACS Chemical …, 2022 - ACS Publications
Glycans are critical to every facet of biology and medicine, from viral infections to
embryogenesis. Tools to study glycans are rapidly evolving; however, the majority of our …

Primary structure of glycans by NMR spectroscopy

C Fontana, G Widmalm - Chemical Reviews, 2023 - ACS Publications
Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …

CHARMM-GUI Membrane Builder for Complex Biological Membrane Simulations with Glycolipids and Lipoglycans

J Lee, DS Patel, J Ståhle, SJ Park… - Journal of chemical …, 2018 - ACS Publications
Glycolipids (such as glycoglycerolipids, glycosphingolipids, and
glycosylphosphatidylinositol) and lipoglycans (such as lipopolysaccharides (LPS) …

Updates to the symbol nomenclature for glycans guidelines

S Neelamegham, K Aoki-Kinoshita, E Bolton… - …, 2019 - academic.oup.com
Abstract The Symbol Nomenclature for Glycans (SNFG) is a community-curated standard for
the depiction of monosaccharides and complex glycans using various colored-coded …

CRISPR screens decode cancer cell pathways that trigger γδ T cell detection

MR Mamedov, S Vedova, JW Freimer, AD Sahu… - Nature, 2023 - nature.com
Abstract γδ T cells are potent anticancer effectors with the potential to target tumours
broadly, independent of patient-specific neoantigens or human leukocyte antigen …

Direct observation of glycans bonded to proteins and lipids at the single-molecule level

K Anggara, L Sršan, T Jaroentomeechai, X Wu… - Science, 2023 - science.org
Proteins and lipids decorated with glycans are found throughout biological entities, playing
roles in biological functions and dysfunctions. Current analytical strategies for these glycan …