Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …

Objective To summarize the role of melatonin and circadian rhythms in determining optimal
female reproductive physiology, especially at the peripheral level. Design Databases were …

The physiology of oocyte in vitro maturation remains elusive. Generally, the oocytes have a
very low maturation rate under in vitro conditions. In the current study, we found that …

Mammalian oocytes and early embryos derived from in vitro production are highly
susceptible to a variety of cellular stresses. During oocyte maturation and preimplantation …

Infertility is an increasing global public health concern with socio-psychological implications
for affected couples. Remarkable advances in reproductive medicine have led to successful …

Significance: Four decades have passed since the first successful human embryo conceived
from a fertilization in vitro. Despite all advances, success rates in assisted reproduction …

Infertility is a major global health issue and male factors account for half of all infertility
cases. One of the causes of male infertility is the loss of spermatogonial stem cells, which …

Free radicals and other reactive species are involved in normal ovarian physiology.
However, they are also highly reactive with complex cellular molecules (proteins, lipids, and …

Pregnancy and lactation are reproductive processes that rely on physiological adaptations
that should be timely and adequately triggered to guarantee both maternal and fetal health …

Objectives Reproductive malfunctions after chemotherapy still are a reason of reducing
fertility and need specialized intensive care. The aim of this review was to investigate the …