Thiazole ring—A biologically active scaffold
A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …
applications. Its derivatives have a wide range of biological activities such as antioxidant …
A review on recent synthetic strategies and pharmacological importance of 1, 3-thiazole derivatives
S Nayak, SL Gaonkar - Mini reviews in medicinal chemistry, 2019 - ingentaconnect.com
Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug
design. Presence of several reaction sites in the thiazole moiety extends their range of …
design. Presence of several reaction sites in the thiazole moiety extends their range of …
Efficient synthesis, antibacterial, antifungal, antioxidant and cytotoxicity study of 2‐(2‐hydrazineyl) thiazole derivatives
VA Adole, RA More, BS Jagdale, TB Pawar… - …, 2020 - Wiley Online Library
In the present investigation, an alluring green PEG‐400 mediated one‐pot synthesis of
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …
In vitro antioxidant activity of thiazolidinone derivatives of 1, 3-thiazole and 1, 3, 4-thiadiazole
M Djukic, M Fesatidou, I Xenikakis, A Geronikaki… - Chemico-Biological …, 2018 - Elsevier
The initial steps in preclinical drug developing research concern the synthesis of new
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …
Medicinal perspective of indole derivatives: recent developments and structure-activity relationship studies
Heterocyclic compounds play a significant role in various biological processes of the human
body and many of them are in clinical use due to their diverse, chemical and biological …
body and many of them are in clinical use due to their diverse, chemical and biological …
Synthesis, molecular docking and QSAR study of thiazole clubbed pyrazole hybrid as α-amylase inhibitor
In search of potent α-amylase inhibitors, herein we report the synthesis, molecular docking
and QSAR study of some thiazole clubbed pyrazole hybrids (TCPH) ie, 1-((1-phenyl-3-aryl-1 …
and QSAR study of some thiazole clubbed pyrazole hybrids (TCPH) ie, 1-((1-phenyl-3-aryl-1 …
[HTML][HTML] Thiazole ring-the antimicrobial, anti-inflammatory, and anticancer active scaffold
S Hosseininezhad, A Ramazani - Arabian Journal of Chemistry, 2023 - Elsevier
Background Thiazole ring is one of the most important heterocycle scaffolds in organic and
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …
Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative …
J Figueiredo, JL Serrano, E Cavalheiro… - European journal of …, 2018 - Elsevier
Barbituric and thiobarbituric acid derivatives have become progressively attractive to
medicinal chemists due to their wide range of biological activities. Herein, different series of …
medicinal chemists due to their wide range of biological activities. Herein, different series of …
Synthesis and antimicrobial activity of new heteroaryl (aryl) thiazole derivatives molecular docking studies
V Kartsev, A Geronikaki, A Zubenko, A Petrou… - Antibiotics, 2022 - mdpi.com
Herein, we report the design, synthesis, and evaluation of the antimicrobial activity of new
heteroaryl (aryl) thiazole derivatives. The design was based on a molecular hybridization …
heteroaryl (aryl) thiazole derivatives. The design was based on a molecular hybridization …
Synthesized thiazole-based hydrazides and their spectral characterization along with biological studies: Promising quantum chemical insights
Hydrazide scaffold is very significant in medicinal and synthetic chemistry. Hydrazides lead
to heterocyclic pharmacophores exhibiting substantial physicochemical properties …
to heterocyclic pharmacophores exhibiting substantial physicochemical properties …