Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

P Intasian, K Prakinee, A Phintha, D Trisrivirat… - Chemical …, 2021 - ACS Publications
Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Microbial production of fatty acids and derivative chemicals

IJ Cho, KR Choi, SY Lee - Current Opinion in Biotechnology, 2020 - Elsevier
Highlights•Microorganisms have been engineered to produce FAs from non-edible carbon
sources.•Non-oleaginous microorganisms were engineered to produce FFAs.•Oleaginous …

Microbial synthesis of long-chain α-alkenes from methanol by engineering Pichia pastoris

P Cai, Y Li, X Zhai, L Yao, X Ma, L Jia… - Bioresources and …, 2022 - Springer
Abstract α-Alkenes (terminal alkenes) are important fuel and platform chemicals that are
mainly produced from petroleum. Microbial synthesis might provide a sustainable approach …

Direct 1,3-butadiene biosynthesis in Escherichia coli via a tailored ferulic acid decarboxylase mutant

Y Mori, S Noda, T Shirai, A Kondo - Nature communications, 2021 - nature.com
Abstract The C4 unsaturated compound 1, 3-butadiene is an important monomer in synthetic
rubber and engineering plastic production. However, microorganisms cannot directly …

[HTML][HTML] Opportunities and challenges for n-alkane and n-alkene biosynthesis: A sustainable microbial biorefinery

J Geng, P Liao, GYA Tan, FY Zhu… - Biofuel Research …, 2023 - biofueljournal.com
Alkanes and alkenes are high-value platform chemicals that can be synthesized by
microorganisms, utilizing organic residues from agri-food industries and municipalities …

Biochemical characterization of three new α-olefin-producing P450 fatty acid decarboxylases with a halophilic property

Y Jiang, Z Li, C Wang, YJ Zhou, H Xu, S Li - Biotechnology for biofuels, 2019 - Springer
Background The CYP152 family member OleT JE from Jeotgalicoccus sp. ATCC 8456 has
been well-known to catalyze the unusual one-step decarboxylation of free fatty acids …

Synthetic metabolic pathway for the production of 1-alkenes from lignin-derived molecules

J Luo, T Lehtinen, E Efimova, V Santala… - Microbial Cell Factories, 2019 - Springer
Background Integration of synthetic metabolic pathways to catabolically diverse chassis
provides new opportunities for sustainable production. One attractive scenario is the use of …

Single mutation at a highly conserved region of chloramphenicol acetyltransferase enables isobutyl acetate production directly from cellulose by Clostridium …

H Seo, JW Lee, S Garcia, CT Trinh - Biotechnology for biofuels, 2019 - Springer
Background Esters are versatile chemicals and potential drop-in biofuels. To develop a
sustainable production platform, microbial ester biosynthesis using alcohol …

[HTML][HTML] Biosynthesis of alkanes/alkenes from fatty acids or derivatives (triacylglycerols or fatty aldehydes)

RRC Monteiro, SSO da Silva, CL Cavalcante Jr… - Biotechnology …, 2022 - Elsevier
This review summarizes the most relevant advances in the biological transformation of fatty
acids (or derivatives) into hydrocarbons to be used as biofuels (biogasoline, green diesel …

The pathway less traveled: engineering biosynthesis of nonstandard functional groups

M Sulzbach, AM Kunjapur - Trends in biotechnology, 2020 - cell.com
The field of metabolic engineering has achieved biochemical routes for conversion of
renewable inputs to structurally diverse chemicals, but these products contain a limited …