Metabolomics: A way forward for crop improvement

A Razzaq, B Sadia, A Raza, M Khalid Hameed… - Metabolites, 2019 - mdpi.com
Metabolomics is an emerging branch of “omics” and it involves identification and
quantification of metabolites and chemical footprints of cellular regulatory processes in …

The progress of multi-omics technologies: determining function in lactic acid bacteria using a systems level approach

ST O'Donnell, RP Ross, C Stanton - Frontiers in microbiology, 2020 - frontiersin.org
Lactic Acid Bacteria (LAB) have long been recognized as having a significant impact
ranging from commercial to health domains. A vast amount of research has been carried out …

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Y Zhou, B Zhou, L Pache, M Chang… - Nature …, 2019 - nature.com
A critical component in the interpretation of systems-level studies is the inference of enriched
biological pathways and protein complexes contained within OMICs datasets. Successful …

WebGestalt 2017: a more comprehensive, powerful, flexible and interactive gene set enrichment analysis toolkit

J Wang, S Vasaikar, Z Shi, M Greer… - Nucleic acids …, 2017 - academic.oup.com
Functional enrichment analysis has played a key role in the biological interpretation of high-
throughput omics data. As a long-standing and widely used web application for functional …

g: Profiler—a web server for functional interpretation of gene lists (2016 update)

J Reimand, T Arak, P Adler, L Kolberg… - Nucleic acids …, 2016 - academic.oup.com
Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse
high-throughput experiments. g: Profiler studies flat and ranked gene lists and finds …

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

A Golebiewska, AC Hau, A Oudin, D Stieber… - Acta …, 2020 - Springer
Patient-based cancer models are essential tools for studying tumor biology and for the
assessment of drug responses in a translational context. We report the establishment a large …

Strong phenotypic plasticity limits potential for evolutionary responses to climate change

V Oostra, M Saastamoinen, BJ Zwaan… - Nature …, 2018 - nature.com
Phenotypic plasticity, the expression of multiple phenotypes from one genome, is a
widespread adaptation to short-term environmental fluctuations, but whether it facilitates …

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

P Hari, FR Millar, N Tarrats, J Birch, A Quintanilla… - Science …, 2019 - science.org
Cellular senescence is a stress response program characterized by a robust cell cycle arrest
and the induction of a proinflammatory senescence-associated secretory phenotype (SASP) …

eVITTA: a web-based visualization and inference toolbox for transcriptome analysis

X Cheng, J Yan, Y Liu, J Wang… - Nucleic acids …, 2021 - academic.oup.com
Transcriptome profiling is essential for gene regulation studies in development and disease.
Current web-based tools enable functional characterization of transcriptome data, but most …

Phantasus, a web application for visual and interactive gene expression analysis

M Kleverov, D Zenkova, V Kamenev, M Sablina… - Elife, 2024 - elifesciences.org
Transcriptomic profiling became a standard approach to quantify a cell state, which led to
the accumulation of huge amount of public gene expression datasets. However, both reuse …