Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines

J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

Effect of low sodium and high potassium diet on lowering blood pressure and cardiovascular events

BS Kim, MY Yu, J Shin - Clinical Hypertension, 2024 - Springer
Incorporating aggressive lifestyle modifications along with antihypertensive medication
therapy is a crucial treatment strategy to enhance the control rate of hypertension. Dietary …

A novel NCI-H69AR drug-resistant small-cell lung cancer mini-tumor model for anti-cancer treatment screening

A van Niekerk, K Wrzesinski, D Steyn, C Gouws - Cells, 2023 - mdpi.com
Small-cell lung cancer is a fast-growing carcinoma with a poor prognosis and a high level of
relapse due to multi-drug resistance (MDR). Genetic mutations that lead to the …

Age‐Dependent impairment in endothelial function and arterial stiffness in former high class male athletes is no different to that in men with no history of physical …

J Majerczak, M Grandys, M Frołow… - Journal of the …, 2019 - Am Heart Assoc
Background Physical activity is generally considered to exert positive effects on the
cardiovascular system in humans. However, surprisingly little is known about the delayed …

Exercise training decreases nitrite concentration in the heart and locomotory muscles of rats without changing the muscle nitrate content

J Majerczak, H Drzymala‐Celichowska… - Journal of the …, 2024 - Am Heart Assoc
Background Skeletal muscles are postulated to be a potent regulator of systemic nitric oxide
homeostasis. In this study, we aimed to evaluate the impact of physical training on the heart …

ABCNet: A new efficient 3D dense‐structure network for segmentation and analysis of body tissue composition on body‐torso‐wide CT images

T Liu, J Pan, DA Torigian, P Xu, Q Miao… - Medical …, 2020 - Wiley Online Library
Purpose Quantification of body tissue composition is important for research and clinical
purposes, given the association between the presence and severity of several disease …

Nitrite concentration in the striated muscles is reversely related to myoglobin and mitochondrial proteins content in rats

J Majerczak, A Kij, H Drzymala-Celichowska… - International Journal of …, 2022 - mdpi.com
Skeletal muscles are an important reservoir of nitric oxide (NO•) stored in the form of nitrite
[NO2−] and nitrate [NO3−](NOx). Nitrite, which can be reduced to NO• under hypoxic and …

Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women

GF da Cruz, TM Lunz, TR de Jesus, MB Costa… - BMC musculoskeletal …, 2021 - Springer
Background The appendicular skeletal muscle mass index (ASMI) is an important risk
indicator for osteoporosis because of the anatomical proximity and metabolic connection …

Effect of Resistance Exercise on Body Composition and Functional Capacity in Older Women with Sarcopenic Obesity—A Systematic Review with Narrative Synthesis

WA Debes, M Sadaqa, Z Németh, A Aldardour… - Journal of Clinical …, 2024 - mdpi.com
Background: Resistance exercise has shown effectiveness in reducing various risk factors
related to sarcopenic obesity (SO) compared to other types of exercise, eg, aerobic exercise …

Evaluating parameters affecting drug fate at the intramuscular injection site

AJS McCartan, DW Curran, RJ Mrsny - Journal of Controlled Release, 2021 - Elsevier
Intramuscular (IM) injections are a well-established method of delivering a variety of
therapeutics formulated for parenteral administration. While the wide range of commercial IM …