Development of novel isatin thiazolyl-pyrazoline hybrids as promising antimicrobials in MDR pathogens
Microbial Multidrug Resistance (MDR) is an emerging global crisis. Derivatization of natural
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …
Synthetic strategies for thiazolopyridine derivatives
MS Nazir, A Nawaz, S Aslam, M Ahmad… - Synthetic …, 2023 - Taylor & Francis
Both thiazole and pyridine are well recognized heterocycles. The fusion of these two
heterocycles results in thiazolopyridine ring system, which is the part of a large number of …
heterocycles results in thiazolopyridine ring system, which is the part of a large number of …
Synthesis, and docking studies of novel heterocycles incorporating the indazolylthiazole moiety as antimicrobial and anticancer agents
NTA Dawoud, EM El-Fakharany, AE Abdallah… - Scientific Reports, 2022 - nature.com
The current study was directed toward developing a new series of fused heterocycles
incorporating indazolylthiazole moiety. The newly synthesized compounds were …
incorporating indazolylthiazole moiety. The newly synthesized compounds were …
Recent advances in the synthesis of thiazolo [4, 5-b] pyridines. Part 2: Focus on thiazole annulation to pyridine ring (microreview)
TI Chaban, OV Klenina, IH Chaban… - Chemistry of Heterocyclic …, 2024 - Springer
Accepted after revision March 27, 2024 in different positions, as well as their ability to
interact with a wider range of receptor targets may become the factors of crucial importance …
interact with a wider range of receptor targets may become the factors of crucial importance …
A New 4-Thiazolidinone Derivative (Les-6490) as a Gut Microbiota Modulator: Antimicrobial and Prebiotic Perspectives
A novel 4-thiazolidinone derivative Les-6490 (pyrazol-4-thiazolidinone hybrid) was
designed, synthesized, and characterized by spectral data. The compound was screened for …
designed, synthesized, and characterized by spectral data. The compound was screened for …
Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3H-thiazolo[4,5-b]pyridin-2-ones
A series of 5-methyl-7-phenyl-3 H-thiazolo [4, 5-b] pyridin-2-ones has been designed,
synthesized, and characterized by spectral data. Target compounds were screened for their …
synthesized, and characterized by spectral data. Target compounds were screened for their …
Functionalization of novel anti-microbial drug based on molecular docking study for nicotinonitrile analogs prepared by microwave irradiation
MA Alsafi, BHA Al-Dhuwayin, WI El-Sofany… - Journal of Molecular …, 2022 - Elsevier
A series of new nicotinonitrile derivatives 3–18 bearing substituents at positions 2, 4, and 6
are prepared under microwave reaction conditions. The higher yields were obtained in a …
are prepared under microwave reaction conditions. The higher yields were obtained in a …
[PDF][PDF] ПОЛІФУНКЦІОНАЛЬНІ КОНДЕНСОВАНІ ТА НЕКОНДЕНСОВАНІ ПОХІДНІ ТІАЗОЛУ/ТІАЗОЛІДИНОНУ: СПРЯМОВАНИЙ СИНТЕЗ, ФІЗИКО-ХІМІЧНІ …
АВ Лозинський - nauka.meduniv.lviv.ua
Дисертаційна робота присвячена спрямованому синтезу нових поліфункціональних
конденсованих та неконденсованих похідних тіазолу/тіазолідинону, вивченню їх фізико …
конденсованих та неконденсованих похідних тіазолу/тіазолідинону, вивченню їх фізико …