Development of novel isatin thiazolyl-pyrazoline hybrids as promising antimicrobials in MDR pathogens

T Al-Warhi, DM Elimam, ZM Elsayed, MM Abdel-Aziz… - RSC …, 2022 - pubs.rsc.org
Microbial Multidrug Resistance (MDR) is an emerging global crisis. Derivatization of natural
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …

Synthetic strategies for thiazolopyridine derivatives

MS Nazir, A Nawaz, S Aslam, M Ahmad… - Synthetic …, 2023 - Taylor & Francis
Both thiazole and pyridine are well recognized heterocycles. The fusion of these two
heterocycles results in thiazolopyridine ring system, which is the part of a large number of …

Synthesis, and docking studies of novel heterocycles incorporating the indazolylthiazole moiety as antimicrobial and anticancer agents

NTA Dawoud, EM El-Fakharany, AE Abdallah… - Scientific Reports, 2022 - nature.com
The current study was directed toward developing a new series of fused heterocycles
incorporating indazolylthiazole moiety. The newly synthesized compounds were …

Recent advances in the synthesis of thiazolo [4, 5-b] pyridines. Part 2: Focus on thiazole annulation to pyridine ring (microreview)

TI Chaban, OV Klenina, IH Chaban… - Chemistry of Heterocyclic …, 2024 - Springer
Accepted after revision March 27, 2024 in different positions, as well as their ability to
interact with a wider range of receptor targets may become the factors of crucial importance …

A New 4-Thiazolidinone Derivative (Les-6490) as a Gut Microbiota Modulator: Antimicrobial and Prebiotic Perspectives

Y Konechnyi, T Rumynska, I Yushyn, S Holota… - Antibiotics, 2024 - mdpi.com
A novel 4-thiazolidinone derivative Les-6490 (pyrazol-4-thiazolidinone hybrid) was
designed, synthesized, and characterized by spectral data. The compound was screened for …

Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3H-thiazolo[4,5-b]pyridin-2-ones

A Lozynskyi, Y Konechnyi, J Senkiv, I Yushyn… - Scientia …, 2021 - mdpi.com
A series of 5-methyl-7-phenyl-3 H-thiazolo [4, 5-b] pyridin-2-ones has been designed,
synthesized, and characterized by spectral data. Target compounds were screened for their …

Functionalization of novel anti-microbial drug based on molecular docking study for nicotinonitrile analogs prepared by microwave irradiation

MA Alsafi, BHA Al-Dhuwayin, WI El-Sofany… - Journal of Molecular …, 2022 - Elsevier
A series of new nicotinonitrile derivatives 3–18 bearing substituents at positions 2, 4, and 6
are prepared under microwave reaction conditions. The higher yields were obtained in a …

[PDF][PDF] ПОЛІФУНКЦІОНАЛЬНІ КОНДЕНСОВАНІ ТА НЕКОНДЕНСОВАНІ ПОХІДНІ ТІАЗОЛУ/ТІАЗОЛІДИНОНУ: СПРЯМОВАНИЙ СИНТЕЗ, ФІЗИКО-ХІМІЧНІ …

АВ Лозинський - nauka.meduniv.lviv.ua
Дисертаційна робота присвячена спрямованому синтезу нових поліфункціональних
конденсованих та неконденсованих похідних тіазолу/тіазолідинону, вивченню їх фізико …