Non-invasive and/or non-destructive techniques can provide structural information about
bone, beyond simple bone densitometry. While the latter provides important information …

The involvement of bone in osteoarthritis has long been thought to be secondary to cartilage
damage as an adaptation of the joint. Recent clinical studies with MRI have demonstrated …

MicroComputed Tomography has become the gold standard for studying 3D microscopic
structures nondestructively, and this book provides up-to-date coverage of the modality. The …

Introduction Osteoporosis (OP) increases cartilage damage in a combined rabbit model of
OP and osteoarthritis (OA). Accordingly, we assessed whether microstructure impairment at …

OBJECTIVE: The pathogenesis of osteoarthritis (OA) includes cartilage degeneration,
synovial inflammation, and bone changes. Slowly, the sequence and inter-relationship of …

Introduction Although the presence of bone marrow lesions (BMLs) on magnetic resonance
images is strongly associated with osteoarthritis progression and pain, the underlying …

Developing effective treatment for osteoarthritis (OA), a prevalent and disabling disease, has
remained a challenge, primarily because of limited understanding of its pathogenesis and …

Despite increasing evidence that subchondral bone contributes to osteoarthritis (OA)
pathogenesis, little is known about local changes in bone structure compared to cartilage …

A bright μm-sized source of hard synchrotron x-rays (critical energy E crit> 30 keV) based on
the betatron oscillations of laser wakefield accelerated electrons has been developed. The …

Objective Few methods exist to measure the progression of osteoarthritis (OA) or to identify
people at high risk of developing OA. Striking radiographic changes include deformation of …