Biostimulants for plant growth and mitigation of abiotic stresses: A metabolomics perspective

L Nephali, LA Piater, IA Dubery, V Patterson, J Huyser… - Metabolites, 2020 - mdpi.com
Adverse environmental conditions due to climate change, combined with declining soil
fertility, threaten food security. Modern agriculture is facing a pressing situation where novel …

To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Systems biology and multi-omics integration: viewpoints from the metabolomics research community

FR Pinu, DJ Beale, AM Paten, K Kouremenos… - Metabolites, 2019 - mdpi.com
The use of multiple omics techniques (ie, genomics, transcriptomics, proteomics, and
metabolomics) is becoming increasingly popular in all facets of life science. Omics …

Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Metabolomics in the context of plant natural products research: From sample preparation to metabolite analysis

MA Salem, L Perez de Souza, A Serag, AR Fernie… - Metabolites, 2020 - mdpi.com
Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

Analytical techniques for metabolomic studies: A review

K Segers, S Declerck, D Mangelings, YV Heyden… - Bioanalysis, 2019 - Taylor & Francis
Metabolomics is the comprehensive study of small-molecule metabolites. Obtaining a wide
coverage of the metabolome is challenging because of the broad range of physicochemical …

Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography–mass spectrometry

F Zheng, X Zhao, Z Zeng, L Wang, W Lv, Q Wang… - Nature protocols, 2020 - nature.com
Untargeted methods are typically used in the detection and discovery of small organic
compounds in metabolomics research, and ultra-high-performance liquid chromatography …

Volatile compounds in human breath: critical review and meta-analysis

T Issitt, L Wiggins, M Veysey, ST Sweeney… - Journal of Breath …, 2022 - iopscience.iop.org
Volatile compounds contained in human breath reflect the inner workings of the body. A
large number of studies have been published that link individual components of breath to …

Phytobioactive compounds as therapeutic agents for human diseases: A review

M Riaz, R Khalid, M Afzal, F Anjum… - Food Science & …, 2023 - Wiley Online Library
Phytobioactive compounds are plant secondary metabolites and bioactive compounds
abundantly present in medicinal plants and have remarkable therapeutic potential. Oxidative …

Advanced tandem mass spectrometry in metabolomics and lipidomics—methods and applications

S Heiles - Analytical and Bioanalytical Chemistry, 2021 - Springer
Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …