Collagen, an abundant extracellular matrix protein, has been found to have a lot of
pharmaceuticals, medicine, food, and cosmetics applications. Increased knowledge of …

Osteoarthritis (OA) is the most common joint disease, generating pain, disability, and
socioeconomic costs worldwide. Currently there are no approved disease-modifying drugs …

Our understanding of the molecular basis for cellular senescence remains incomplete,
limiting the development of strategies to ameliorate age-related pathologies by preventing …

Aging is a multifactorial and natural process that causes physiological changes in organs,
tissues and cells over time. In the skin and cartilage, aging leads to a decrease in the …

Although role of the microbiome in osteoarthritis is an area of intense study, no clear
mechanism of action has been determined. Increased understanding of how the two factors …

Collagen is one of the main components of the extracellular matrix of the dermis and
articular cartilage and influences the body's mechanical, organizational, and tissue …

Introduction There is currently no disease-modifying drug for osteoarthritis (OA), and some
safety concerns have been identified about the leading traditional drugs. Therefore …

This study examined whether consuming collagen peptides (CP) before and after strenuous
exercise alters markers of muscle damage, inflammation and bone turnover. Using a double …

Collagen is characterized by its high content of glycine, proline and hydroxyproline, and is
found to exert beneficial effects on joint pain related to activity and osteoarthritis. However, to …

ABSTRACT RUNX2 is a transcription factor critical for chondrocyte maturation and normal
endochondral bone formation. It promotes the expression of factors catabolic to the cartilage …