Fluorescent organic small molecule probes for bioimaging and detection applications
Y Yang, F Gao, Y Wang, H Li, J Zhang, Z Sun, Y Jiang - Molecules, 2022 - mdpi.com
The activity levels of key substances (metal ions, reactive oxygen species, reactive nitrogen,
biological small molecules, etc.) in organisms are closely related to intracellular redox …
biological small molecules, etc.) in organisms are closely related to intracellular redox …
Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics
Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet,
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …
Photophysical engineering of fluorescent proteins: Accomplishments and challenges of physical chemistry strategies
S Mukherjee, R Jimenez - The Journal of Physical Chemistry B, 2022 - ACS Publications
Fluorescent proteins (FPs) have become ubiquitous tools for biological research and
concomitantly they are intriguing molecules that are amenable to study with a wide range of …
concomitantly they are intriguing molecules that are amenable to study with a wide range of …
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans
Over the past decade, immunotherapy delivered novel treatments for many cancer types.
However, lung cancer still leads cancer mortality, and non-small-cell lung carcinoma …
However, lung cancer still leads cancer mortality, and non-small-cell lung carcinoma …
Bridging high resolution sub-cellular imaging with physiologically relevant engineered tissues
Y Kargar Gaz Kooh, N Huebsch - Frontiers in Mechanical …, 2024 - frontiersin.org
While high-resolution microscopic techniques are crucial for studying cellular structures in
cell biology, obtaining such images from thick 3D engineered tissues remains challenging …
cell biology, obtaining such images from thick 3D engineered tissues remains challenging …
3D active stabilization for single-molecule imaging
A key part of any super-resolution technique involves accurately correcting for mechanical
motion of the sample and setup during acquisition. If left uncorrected, drift degrades the …
motion of the sample and setup during acquisition. If left uncorrected, drift degrades the …
The use of fluorescence lifetime imaging (FLIM) for in situ microbial detection in complex mineral substrates
Y Chmykh, JL Nadeau - Journal of Microscopy, 2024 - Wiley Online Library
The utility of fluorescence lifetime imaging microscopy (FLIM) for identifying bacteria in
complex mineral matrices was investigated. Baseline signals from unlabelled Bacillus …
complex mineral matrices was investigated. Baseline signals from unlabelled Bacillus …
Research on the transition dynamics and linear (nonlinear) optical properties of mCherry
Y Wang, G Li, J Dai, X Peng, Q Zhao - arXiv preprint arXiv:2304.11047, 2023 - arxiv.org
In this study, we explore the electron transition mechanism and optical properties of the
popular red fluorescent protein mCherry. By examining the charge transfer spectrum and …
popular red fluorescent protein mCherry. By examining the charge transfer spectrum and …
Building a Total Internal Reflection Microscope (TIRF) with Active Stabilization (Feedback SMLM)
The data quality of high-resolution imaging can be markedly improved with active
stabilization, which is based on feedback loops within the microscope that maintain the …
stabilization, which is based on feedback loops within the microscope that maintain the …
[PDF][PDF] Personal Contribution
Two-photon excited fluorescence lifetime imaging (2P-FLIM) combined with genetically
encoded sensors (GESs) can greatly improve our understanding of metabolic processes in …
encoded sensors (GESs) can greatly improve our understanding of metabolic processes in …