Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
Multifarious roles of sialic acids in immunity
Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …
The cellular and molecular basis for malaria parasite invasion of the human red blood cell
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
The pathogenic basis of malaria
LH Miller, DI Baruch, K Marsh, OK Doumbo - Nature, 2002 - nature.com
Malaria is today a disease of poverty and underdeveloped countries. In Africa, mortality
remains high because there is limited access to treatment in the villages. We should follow …
remains high because there is limited access to treatment in the villages. We should follow …
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes
X Su, VM Heatwole, SP Wertheimer, F Guinet… - Cell, 1995 - cell.com
The human malaria parasite Plasmodium faiciparum evades host immunity by varying the
antigenic and adhesive character of infected erythrocytes. We describe a large and …
antigenic and adhesive character of infected erythrocytes. We describe a large and …
Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes
Plasmodium falciparum expresses on the host erythrocyte surface clonally variant antigens
and ligands that mediate adherence to endothelial receptors. Both are central to …
and ligands that mediate adherence to endothelial receptors. Both are central to …
Plasmodium vivax clinical malaria is commonly observed in Duffy-negative Malagasy people
D Ménard, C Barnadas, C Bouchier… - Proceedings of the …, 2010 - National Acad Sciences
Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …
Receptor and Ligand Domains for Invasion of Erythrocytes by Plasmodium falciparum
BKL Sim, CE Chitnis, K Wasniowska, TJ Hadley… - Science, 1994 - science.org
A 175-kilodalton erythrocyte binding protein, EBA-175, of the parasite Plasmodium
falciparum mediates the invasion of erythrocytes. The erythrocyte receptor for EBA-175 is …
falciparum mediates the invasion of erythrocytes. The erythrocyte receptor for EBA-175 is …
Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion.
CE Chitnis, LH Miller - The Journal of experimental medicine, 1994 - rupress.org
Plasmodium vivax and the related monkey malaria, P. knowlesi, require interaction with the
Duffy blood group antigen, a receptor for a family of chemokines that includes interleukin 8 …
Duffy blood group antigen, a receptor for a family of chemokines that includes interleukin 8 …