K elch‐like ECH‐associated protein 1 (K eap1)‐nuclear factor erythroid 2‐related factor 2 (N
rf2)‐antioxidant response elements (ARE) pathway represents one of the most important …

Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Glutathione peroxidase and thioredoxin reductase are major selenoenzymes through which
selenium exerts powerful antioxidant effects. Selenium also elicits pro-oxidant effects at toxic …

Selenium (Se) is an essential trace element with a narrow margin between beneficial and
toxic effects. As a promising chemopreventive agent, its use requires consumption over the …

Significance: All cells must maintain a balance between oxidants and reductants, while
allowing for fluctuations in redox states triggered by signaling, altered metabolic flow, or …

Beta-amyloid (Aβ) peptide, the hallmark of Alzheimer's disease, invokes oxidative damage
to neurons and eventually leads to neuronal death. Selenylation modification of …

It has been shown that 36nm Nano-Se has lower toxicity than selenite or selenomethionine,
but these forms of selenium (Se) all possess similar ability to increase selenoenzyme levels …

Selenium represents an essential element for organisms as various diseases can result from
selenium deficiency. As a consequence, selenium-containing heterocycles are of …

The role of selenium as potential cancer chemopreventive and chemotherapeutic agents
has been supported by epidemiological, preclinical and clinical studies. Although cell …

Cadmium (Cd) is a ubiquitously distributed trace metal and environmental pollutant that is
highly toxic to liver. Selenium (Se) may provide chemoprotection against Cd-induced …