Suspected non-Alzheimer disease pathophysiology (SNAP) is a biomarker-based concept
that applies to individuals with normal levels of amyloid-β biomarkers in the brain, but in …

The hippocampus is particularly vulnerable to the neurotoxic effects of obesity, diabetes
mellitus, hypertension, hypoxic brain injury, obstructive sleep apnoea, bipolar disorder …

We recently demonstrated that the frequencies of biomarker groups defined by the presence
or absence of both amyloidosis (A+) and neurodegeneration (N+) changed dramatically by …

The human hippocampus is vulnerable to a range of degenerative conditions and as such,
accurate in vivo measurement of the hippocampus and hippocampal substructures via …

This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2017. Other selected articles can be found online at http://ccforum …

The medial temporal lobes (MTLs) are critical for episodic memory but the functions of MTL
subregions are controversial. According to memory strength theory, MTL subregions …

Research has firmly established that the integrity of the medial temporal lobe (MTL) is critical
for recognition memory. This ability is supported by recollection, which involves recovery of …

Sepsis-associated encephalopathy (SAE), a major complication of sepsis, is characterized
by impaired consciousness, including delirium and coma. Additionally SAE associates with …

This study investigates relationships between white matter hyperintensity (WMH) volume,
cerebrospinal fluid (CSF) Alzheimer's disease (AD) pathology markers, and brain and …

Increasing evidence suggests that cognitive function improves during a single bout of
moderate exercise. In contrast, exercise under hypoxia may compromise the availability of …