Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review

RY Gan, HB Li, ZQ Sui, H Corke - Critical reviews in food science …, 2018 - Taylor & Francis
Green tea is one of the most popular beverages in the world, especially in Asian countries.
Consumption of green tea has been demonstrated to possess many health benefits, which …

A long journey into aging, brain aging, and Alzheimer's disease following the oxidative stress tracks

P Mecocci, V Boccardi, R Cecchetti… - Journal of …, 2018 - content.iospress.com
Abstract The Editors of the Journal of Alzheimer's Disease invited Professor Patrizia Mecocci
to contribute a review article focused on the importance and implications of her research on …

An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations

KC Kregel, HJ Zhang - American Journal of Physiology …, 2007 - journals.physiology.org
Aging is an inherently complex process that is manifested within an organism at genetic,
molecular, cellular, organ, and system levels. Although the fundamental mechanisms are …

[HTML][HTML] Roles of matrix metalloproteinases in tumor metastasis and angiogenesis

SO Yoon, SJ Park, CH Yun, AS Chung - BMB Reports, 2003 - koreascience.kr
Matrix metalloproteinases (MMPs), zinc dependent proteolytic enzymes, cleave extracellular
matrix (ECM: collagen, laminin, firbronectin, etc) as well as non-matrix substrates (growth …

Size-mediated cytotoxicity and apoptosis of hydroxyapatite nanoparticles in human hepatoma HepG2 cells

Y Yuan, C Liu, J Qian, J Wang, Y Zhang - Biomaterials, 2010 - Elsevier
Hydroxyapatite nanoparticles (HAPN) have been discovered to exert cytotoxicity and
apoptosis-induction in some cancer cells. But it is still not clear how tumor cells interact with …

Biomimetic redox-responsive prodrug micelles with diselenide linkage for platinum nanozymes augmented sonodynamic/chemo combined therapy of colon cancer

Y Zhao, J Xu, Y Zhang, F Wu, W Zhao, R Li… - Chemical Engineering …, 2023 - Elsevier
Due to the complexity of tumorigenesis, it is hard to completely cure tumors with a single
tumor therapy. Combined sonodynamic therapy and chemotherapy (sono-chemotherapy) …

Aging of the brain, entropy, and Alzheimer disease

DA Drachman - Neurology, 2006 - AAN Enterprises
Sporadic Alzheimer disease (AD) is related to advancing age far more than to any other risk
factor and ultimately affects almost half of the population over age 85. Despite its remarkable …

In vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cells

X Lu, J Qian, H Zhou, Q Gan, W Tang, J Lu… - International journal …, 2011 - Taylor & Francis
Background Silica nanoparticles have been discovered to exert cytotoxicity and induce
apoptosis in normal human cells. However, until now, few studies have investigated the …

[PDF][PDF] [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells

YJ Park, J Wen, S Bang, SW Park… - Yonsei medical …, 2006 - synapse.koreamed.org
[6]-Gingerol, a major phenolic compound derived from ginger, has anti-bacterial, anti-
inflammatory and anti-tumor activities. While several molecular mechanisms have been …

Relationship between tau pathology and neuroinflammation in Alzheimer's disease

MJ Metcalfe… - Mount Sinai Journal of …, 2010 - Wiley Online Library
Alzheimer's disease is a chronic, age‐related neurodegenerative disorder. Neurofibrillary
tangles are among the pathological hallmarks of Alzheimer's disease. Neurofibrillary tangles …