Measuring DNA modifications with the comet assay: a compendium of protocols
A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results
The comet assay is a widely used test for the detection of DNA damage and repair activity.
However, there are interlaboratory differences in reported levels of baseline and induced …
However, there are interlaboratory differences in reported levels of baseline and induced …
Comet assay: a versatile but complex tool in genotoxicity testing
E Cordelli, M Bignami, F Pacchierotti - Toxicology Research, 2021 - academic.oup.com
The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It
can also be applied to cells isolated from treated animals. In this review, we highlight …
can also be applied to cells isolated from treated animals. In this review, we highlight …
[HTML][HTML] Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer
G Borrego-Soto, R Ortiz-López… - Genetics and molecular …, 2015 - SciELO Brasil
Breast cancer is the most common malignancy in women. Radiotherapy is frequently used in
patients with breast cancer, but some patients may be more susceptible to ionizing radiation …
patients with breast cancer, but some patients may be more susceptible to ionizing radiation …
The essential comet assay: a comprehensive guide to measuring DNA damage and repair
A Azqueta, AR Collins - Archives of toxicology, 2013 - Springer
The comet assay (single cell gel electrophoresis) is the most common method for measuring
DNA damage in eukaryotic cells or disaggregated tissues. The assay depends on the …
DNA damage in eukaryotic cells or disaggregated tissues. The assay depends on the …
[HTML][HTML] In vivo toxicity of cationic micelles and liposomes
KB Knudsen, H Northeved, PK Ek, A Permin… - … , Biology and Medicine, 2015 - Elsevier
This study investigated toxicity of nanocarriers comprised of cationic polymer and lipid
components often used in gene and drug delivery, formulated as cationic micelles and …
components often used in gene and drug delivery, formulated as cationic micelles and …
Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles
P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …
via production of reactive oxygen species (ROS) and inflammation. We investigated this …
Genotoxicity of particles from grinded plastic items in Caco-2 and HepG2 cells
M Roursgaard, M Hezareh Rothmann… - Frontiers in Public …, 2022 - frontiersin.org
Large plastic litters degrade in the environment to micro-and nanoplastics, which may then
enter the food chain and lead to human exposure by ingestion. The present study explored …
enter the food chain and lead to human exposure by ingestion. The present study explored …
Application of the comet assay in human biomonitoring: An hCOMET perspective
The comet assay is a well-accepted biomonitoring tool to examine the effect of dietary,
lifestyle, environmental and occupational exposure on levels of DNA damage in human …
lifestyle, environmental and occupational exposure on levels of DNA damage in human …
DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death
The comet assay or single cell gel electrophoresis, is the most common method used to
measure strand breaks and a variety of other DNA lesions in human populations. To …
measure strand breaks and a variety of other DNA lesions in human populations. To …