Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

M Erdem Büyükkiraz, Z Kesmen - Journal of applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …

Microbial diseases of bivalve mollusks: infections, immunology and antimicrobial defense

C Zannella, F Mosca, F Mariani, G Franci, V Folliero… - Marine drugs, 2017 - mdpi.com
A variety of bivalve mollusks (phylum Mollusca, class Bivalvia) constitute a prominent
commodity in fisheries and aquacultures, but are also crucial in order to preserve our …

Biofilms: Novel strategies based on antimicrobial peptides

E Galdiero, L Lombardi, A Falanga, G Libralato… - Pharmaceutics, 2019 - mdpi.com
The problem of drug resistance is very worrying and ever increasing. Resistance is due not
only to the reckless use of antibiotics but also to the fact that pathogens are able to adapt to …

Perspectives for clinical use of engineered human host defense antimicrobial peptides

ME Pachón-Ibáñez, Y Smani, J Pachon… - FEMS microbiology …, 2017 - academic.oup.com
Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

Marine antimicrobial peptides: nature provides templates for the design of novel compounds against pathogenic bacteria

A Falanga, L Lombardi, G Franci, M Vitiello… - International journal of …, 2016 - mdpi.com
The discovery of antibiotics for the treatment of bacterial infections brought the idea that
bacteria would no longer endanger human health. However, bacterial diseases still …

A new hope: self-assembling peptides with antimicrobial activity

L Lombardi, A Falanga, V Del Genio, S Galdiero - Pharmaceutics, 2019 - mdpi.com
Peptide drugs hold great promise for the treatment of infectious diseases thanks to their
novel mechanisms of action, low toxicity, high specificity, and ease of synthesis and …

Enhancing the potency of antimicrobial peptides through molecular engineering and self-assembly

L Lombardi, Y Shi, A Falanga, E Galdiero… - …, 2019 - ACS Publications
Healthcare-associated infections resulting from bacterial attachment and biofilm formation
on medical implants are posing significant challenges in particular with the emergence of …

Cyclic peptides as novel therapeutic microbicides: engineering of human defensin mimetics

A Falanga, E Nigro, MG De Biasi, A Daniele, G Morelli… - Molecules, 2017 - mdpi.com
Cyclic peptides are receiving significant attention thanks to their antimicrobial activity and
high serum stability, which is useful to develop and design novel antimicrobial agents …

Peptide-lipid interactions: experiments and applications

S Galdiero, A Falanga, M Cantisani, M Vitiello… - International journal of …, 2013 - mdpi.com
The interactions between peptides and lipids are of fundamental importance in the
functioning of numerous membrane-mediated cellular processes including antimicrobial …

WMR peptide as antifungal and antibiofilm against albicans and non-albicans Candida species: Shreds of evidence on the mechanism of action

A Maione, R Bellavita, E de Alteriis, S Galdiero… - International Journal of …, 2022 - mdpi.com
Candida species are the most common fungal pathogens infecting humans and can cause
severe illnesses in immunocompromised individuals. The increased resistance of Candida …