Biomimetic whitlockite inorganic nanoparticles-mediated in situ remodeling and rapid bone regeneration

HD Kim, HL Jang, HY Ahn, HK Lee, J Park, E Lee… - Biomaterials, 2017 - Elsevier
Bone remodeling process relies on complex signaling pathway between osteoblasts and
osteoclasts and control mechanisms to achieve homeostasis of their growth and …

An overview of modelling craniosynostosis using the finite element method

O Malde, J Libby, M Moazen - Molecular syndromology, 2019 - karger.com
Craniosynostosis is a medical condition caused by the early fusion of the cranial joint. The
finite element method (FEM) is a computational technique that can answer a variety of “what …

Modelling human skull growth: a validated computational model

J Libby, A Marghoub, D Johnson… - Journal of the …, 2017 - royalsocietypublishing.org
During the first year of life, the brain grows rapidly and the neurocranium increases to about
65% of its adult size. Our understanding of the relationship between the biomechanical …

[HTML][HTML] A computational framework to predict calvarial growth: optimising management of sagittal craniosynostosis

C Cross, RH Khonsari, G Patermoster… - … in Bioengineering and …, 2022 - frontiersin.org
The neonate skull consists of several bony plates, connected by fibrous soft tissue called
sutures. Premature fusion of sutures is a medical condition known as craniosynostosis …

[HTML][HTML] Unravelling the structural variation of lizard osteoderms

A Marghoub, CJA Williams, JV Leite, AC Kirby, L Kéver… - Acta Biomaterialia, 2022 - Elsevier
Vertebrate skin is a remarkable organ that supports and protects the body. It consists of two
layers, the epidermis and the underlying dermis. In some tetrapods, the dermis includes …

Form–function relationships underlie rapid dietary changes in a lizard

M Taverne, PJ Watson, H Dutel… - … of the Royal …, 2023 - royalsocietypublishing.org
Macroevolutionary changes such as variation in habitat use or diet are often associated with
convergent, adaptive changes in morphology. However, it is still unclear how small-scale …

[HTML][HTML] Mechanical loading of cranial joints minimizes the craniofacial phenotype in Crouzon syndrome

M Moazen, M Hejazi, D Savery, D Jones… - Scientific Reports, 2022 - nature.com
Children with syndromic forms of craniosynostosis undergo a plethora of surgical
interventions to resolve the clinical features caused by the premature fusion of cranial …

[HTML][HTML] The growth of the buccal mass in Sepia officinalis: functional changes throughout ontogeny

L Souquet, O Basuyaux, G Guichard, A Herrel, I Rouget… - Marine Biology, 2023 - Springer
Due to their small size, juveniles are more likely to show lower absolute levels of
performance leading to a potential competitive disadvantage compared to adults. Therefore …

The role of cranial osteoderms on the mechanics of the skull in scincid lizards

A Marghoub, L Kéver, CJA Williams… - The Anatomical …, 2023 - Wiley Online Library
Osteoderms (ODs) are calcified organs formed directly within the skin of most major extant
tetrapod lineages. Lizards possibly show the greatest diversity in ODs morphology and …

Dimensional, geometrical, and physical constraints in skull growth

J Weickenmeier, C Fischer, D Carter, E Kuhl, A Goriely - Physical review letters, 2017 - APS
After birth, the skull grows and remodels in close synchrony with the brain to allow for an
increase in intracranial volume. Increase in skull area is provided primarily by bone …