Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms

H Zou, H Zhou, R Yan, Z Yao, Q Lu - Frontiers in neuroscience, 2022 - frontiersin.org
The circadian rhythm is crucial for physiological and behavioral functions. Chronotype,
which represents individual preferences for activity and performance, is associated with …

Circadian regulation of depression: A role for serotonin

RA Daut, LK Fonken - Frontiers in neuroendocrinology, 2019 - Elsevier
Synchronizing circadian (24 h) rhythms in physiology and behavior with the environmental
light-dark cycle is critical for maintaining optimal health. Dysregulation of the circadian …

Circadian rhythm disruption in critically ill patients

M Felten, C Dame, G Lachmann, C Spies… - Acta …, 2023 - Wiley Online Library
Patients admitted to the intensive care unit (ICU) are in need of continuous organ
replacement strategies and specialized care, for example because of neurological …

Light and circadian signaling pathway in pregnancy: Programming of adult health and disease

CN Hsu, YL Tain - International journal of molecular sciences, 2020 - mdpi.com
Light is a crucial environmental signal that affects elements of human health, including the
entrainment of circadian rhythms. A suboptimal environment during pregnancy can increase …

Circadian clock genes are regulated by rhythmic corticosterone at physiological levels in the Rat Hippocampus

T Bering, AS Blancas-Velazquez, MF Rath - Neuroendocrinology, 2023 - karger.com
Introduction: In the hippocampus, clock gene expression is important for memory and mood;
however, the signaling mechanism controlling clock gene expression in the hippocampus is …

Patterns of activity correlate with symptom severity in major depressive disorder patients

S Spulber, F Elberling, J Svensson, M Tiger… - Translational …, 2022 - nature.com
Objective measures, such as activity monitoring, can potentially complement clinical
assessment for psychiatric patients. Alterations in rest–activity patterns are commonly …

Epigenetic basis of neuronal and synaptic plasticity

NN Karpova, AJ Sales, SR Joca - Current Topics in Medicinal …, 2017 - ingentaconnect.com
Neuronal network and plasticity change as a function of experience. Altered neural
connectivity leads to distinct transcriptional programs of neuronal plasticity-related genes …

Human Derived Dermal Fibroblasts as in Vitro Research Tool to Study Circadian Rhythmicity in Psychiatric Disorders

D Palm, A Uzoni, G Kronenberg, J Thome… - …, 2023 - thieme-connect.com
A number of psychiatric disorders are defined by persistent or recurrent sleep-wake
disturbances alongside disruptions in circadian rhythm and altered clock gene expression …

Regulation of circadian genes by the MAPK pathway: implications for rapid antidepressant action

XL Wang, K Yuan, W Zhang, SX Li, GF Gao, L Lu - Neuroscience bulletin, 2020 - Springer
Accumulating evidence suggests that the circadian rhythm plays a critical role in mood
regulation, and circadian disturbances are often found in patients with major depressive …

Depressive-like phenotype induced by prenatal dexamethasone in mice is reversed by desipramine

M Conti, S Spulber, M Raciti, S Ceccatelli - Neuropharmacology, 2017 - Elsevier
Exposure to prenatal insults has been associated with an increased risk for neuropsychiatric
disorders, including depression, but the mechanisms are still poorly understood. Persistent …