Fracture healing in osteoporotic bone

WH Cheung, T Miclau, SKH Chow, FF Yang, V Alt - Injury, 2016 - Elsevier
As the world population rises, osteoporotic fracture is an emerging global threat to the well-
being of elderly patients. The process of fracture healing by intramembranous ossification …

[PDF][PDF] Overview: animal models of osteopenia and osteoporosis

WS Jee, W Yao - J Musculoskelet Neuronal Interact, 2001 - ismni.org
Prior to initiating a clinical trial in a post-menopausal osteoporosis study, it is reasonable to
recommence the evaluation of treatment in the 9-month-old ovariectomized female rat. A …

[PDF][PDF] Animal models of osteoporosis—necessity and limitations

AS Turner - Eur Cell Mater, 2001 - ecmjournal.org
There is a great need to further characterise the available animal models for
postmenopausal osteoporosis, for the understanding of the pathogenesis of the disease …

Animal models for fracture treatment in osteoporosis

M Egermann, J Goldhahn, E Schneider - Osteoporosis international, 2005 - Springer
Demographic changes in the age structure of occidental populations are giving rise to
osteoporosis and associated fractures, which are becoming a major public health burden …

Antiosteoporotic effect of ethanol extract of Cissus quadrangularis Linn. on ovariectomized rat

A Shirwaikar, S Khan, S Malini - Journal of Ethnopharmacology, 2003 - Elsevier
Ethanol extract of Cissus quadrangularis was evaluated for its anti-osteoporotic activity in
ovariectomized rat model of osteoporosis at two different dose levels of 500 and 750mg/kg …

Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia

T Jämsä, P Jalovaara, Z Peng, HK Väänänen… - Bone, 1998 - Elsevier
We compared the mechanical and densitometric testing methods in evaluating the
mechanical strength of mouse cortical bones. The femora and tibiae of 10 male mice (weight …

Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing

T Matsumoto, A Kawamoto, R Kuroda… - The American journal of …, 2006 - Elsevier
Failures in fracture healing are mainly caused by a lack of vascularization. Adult human
circulating CD34+ cells, an endothelial/hematopoietic progenitor-enriched cell population …

Antiosteoporotic activity of icariin in ovariectomized rats

H Nian, MH Ma, SS Nian, LL Xu - Phytomedicine, 2009 - Elsevier
Icariin was evaluated for its antiosteoporotic activity in an ovariectomized rat model of
osteoporosis. The rats were divided into sham and OVX groups. The OVX rats were then …

Effect of ethanol extract of Lepidium meyenii Walp. on osteoporosis in ovariectomized rat

Y Zhang, L Yu, M Ao, W Jin - Journal of ethnopharmacology, 2006 - Elsevier
Maca (Lepidium meyenii Walp.) is a cruciferous plant from the Andes of Peru. The root of
Maca is traditionally employed for its supposed properties in aphrodisiacs and improving …

Mineral changes in osteoporosis: a review

D Faibish, SM Ott, AL Boskey - Clinical Orthopaedics and Related …, 2006 - journals.lww.com
Bone mineral composition, crystallinity, and bone mineral content of osteoporotic patients
are different from those of normal subjects. We review the evidence that these mineralization …