The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysis
LF Johnson, DA Lewis - Sexually transmitted diseases, 2008 - journals.lww.com
Materials and Methods The PubMed, Embase and AIDSearch databases were searched on
January 8, 2007 using the following search terms:(HIV or human immunodeficiency virus) …
January 8, 2007 using the following search terms:(HIV or human immunodeficiency virus) …
Sex-based differences in HIV type 1 pathogenesis
MM Addo, M Altfeld - The Journal of infectious diseases, 2014 - academic.oup.com
Human immunodeficiency virus (HIV) remains a global infectious diseases threat that
disproportionally affects women. Beyond social and political factors, biological and genetic …
disproportionally affects women. Beyond social and political factors, biological and genetic …
Increased risk of HIV-1 transmission in pregnancy: a prospective study among African HIV-1-serodiscordant couples
Background: Physiologic and behavioral changes during pregnancy may alter HIV-1
susceptibility and infectiousness. Prospective studies exploring pregnancy and HIV-1 …
susceptibility and infectiousness. Prospective studies exploring pregnancy and HIV-1 …
Regulation of mucosal immunity in the female reproductive tract: the role of sex hormones in immune protection against sexually transmitted pathogens
CR Wira, JV Fahey, M Rodriguez‐Garcia… - American journal of …, 2014 - Wiley Online Library
The immune system in the female reproductive tract (FRT) does not mount an attack against
human immunodeficiency virus (HIV) or other sexually transmitted infections (STI) with a …
human immunodeficiency virus (HIV) or other sexually transmitted infections (STI) with a …
Recent observations on HIV type-1 infection in the genital tract of men and women
RW Coombs, PS Reichelderfer, AL Landay - Aids, 2003 - journals.lww.com
The ultimate success of strategies to prevent sexual transmission of HIV depends, in part, on
a better understanding of the virological and immunological mechanisms that define sexual …
a better understanding of the virological and immunological mechanisms that define sexual …
Determinants of HIV-1 shedding in the genital tract of women
A Kovacs, SS Wasserman, D Burns, DJ Wright, J Cohn… - The Lancet, 2001 - thelancet.com
Summary Background Plasma HIV-1 RNA concentration has been the best predictor for risk
of heterosexual and perinatal transmission. However, direct contact with HIV-1 present …
of heterosexual and perinatal transmission. However, direct contact with HIV-1 present …
Anti-HIV activity in cervical-vaginal secretions from HIV-positive and-negative women correlate with innate antimicrobial levels and IgG antibodies
Background We investigated the impact of antimicrobials in cervicovaginal lavage (CVL)
from HIV (+) and HIV (−) women on target cell infection with HIV. Since female reproductive …
from HIV (+) and HIV (−) women on target cell infection with HIV. Since female reproductive …
Trappin‐2/Elafin: a novel innate anti‐human immunodeficiency virus‐1 molecule of the human female reproductive tract
Trappin‐2/Elafin is a serine protease inhibitor that plays a major role as an anti‐
inflammatory mediator at mucosal surfaces. In addition, Trappin‐2/Elafin has antibacterial …
inflammatory mediator at mucosal surfaces. In addition, Trappin‐2/Elafin has antibacterial …
[HTML][HTML] 17β-Estradiol inhibits HIV-1 by inducing a complex formation between β-catenin and estrogen receptor α on the HIV promoter to suppress HIV transcription
EL Szotek, SD Narasipura, L Al-Harthi - Virology, 2013 - Elsevier
Human Immunodeficiency virus type 1 (HIV-1) disproportionately affects women, accounting
for> 50% of new HIV infections in adults worldwide. While multiple mechanisms may …
for> 50% of new HIV infections in adults worldwide. While multiple mechanisms may …
Estradiol Reduces Susceptibility of CD4+ T Cells and Macrophages to HIV-Infection
M Rodriguez-Garcia, N Biswas, MV Patel, FD Barr… - PloS one, 2013 - journals.plos.org
The magnitude of the HIV epidemic in women requires urgent efforts to find effective
preventive methods. Even though sex hormones have been described to influence HIV …
preventive methods. Even though sex hormones have been described to influence HIV …