The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …

Endoplasmic reticulum (ER) is the major site of protein folding and calcium storage. Beside
the role of ER in protein homeostasis, it controls the cholesterol production and lipid …

Upon stress challenges, proteins/RNAs undergo liquid–liquid phase separation (LLPS) to
fine-tune cell physiology and metabolism to help cells adapt to adverse environments. The …

In most mammalian species including cattle, heat stress has detrimental effects on ovarian
function through disturbing estradiol production and viability of granulosa cells. However …

Spermatogenesis, an intricate process occurring in the testis, is responsible for ongoing
production of spermatozoa and thus the cornerstone of lifelong male fertility. In the testis …

Endoplasmic reticulum (ER) stress, defined as prolonged disturbances in protein folding and
accumulation of unfolded proteins in the ER. Perturbation of the ER, such as distribution of …

Background and aims Today, it has been shown that diabetes mellitus (DM) can affect male
fertility. Glucose metabolism is a vital process in spermatogenesis that is impacted by …

Normal spermatogenic processes require the scrotal temperature to be lower than that of the
body as excessive heat affects spermatogenesis in the testes, reduces sperm quality and …

It has been reported that N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone
(6PPD-Q), a derivative of the tire antioxidant, N-(1, 3-dimethylbutyl)-N′-phenyl-p …

Cisplatin, despite its anti-cancer ability, exhibits severe testicular toxicities when applied
systemically. Due to its wide application in cancer treatment, reduction of its damages to …