Sickle cell hemoglobin

AK Mandal, A Mitra, R Das - … Proteins, Lipoproteins and other Body Fluid …, 2020 - Springer
Sickle cell hemoglobin (HbS) is an example of a genetic variant of human hemoglobin
where a point mutation in the β globin gene results in substitution of glutamic acid to valine …

[HTML][HTML] Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease

CE Kuczynski, CD Porada, A Atala, SS Cho… - Scientific Reports, 2024 - nature.com
Sickle cell disease (SCD) affects millions worldwide, yet there are few therapeutic options.
To develop effective treatments, preclinical models that recapitulate human physiology and …

Nuevos aspectos moleculares y fisiopatológicos de la anemia drepanocítica

GS Noda, LZE Muñoz, KP Leyva - Revista Cubana de Medicina, 2021 - medigraphic.com
Introducción: La enfermedad por hemoglobina S es una anemia hemolítica crónica
hereditaria cuyas manifestaciones clínicas provienen de la tendencia de esta hemoglobina …

Effect of point mutation on structure–function correlation of hemoglobin variants, HbE and HbD Punjab

S Narayanan, B Mathew, BY Srinivasu, V Bhat, C Ross… - Amino Acids, 2020 - Springer
Hemoglobinopathies are examples of autosomal recessive disorders of human hemoglobin.
Hemoglobin E (HbE) and Hemoglobin D Punjab (HbD Punjab) are two of the most common …

New molecular and pathophysiological aspects of sickle cell anemia

GS Noda, LZE Muñoz, KP Leyva - Revista Cubana de Medicina, 2021 - medigraphic.com
Introduction: Hemoglobin S disease is a hereditary chronic hemolytic anemia whose clinical
manifestations come from the tendency of this hemoglobin to polymerize and deform …