Triazoles find applications in several major technological areas, and especially in drug
discovery. The click-chemistry approaches based on Huisgen's cycloaddition reaction are …

The copper‐catalyzed alkyne‐azide cycloaddition (CuAAC) is a highly versatile,
regioselective synthesis of 1, 4‐disubstituted 1, 2, 3‐triazoles under mild reaction conditions …

The copper (I)‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction regiospecifically
produces 1, 4‐disubstituted‐1, 2, 3‐triazole molecules. This heterocycle formation chemistry …

The cyclization reactions of alkynes have become one of the most important and useful
methodologies for the preparation of heterocycles. To this end, the association between …

Trisubstituted 1, 2, 3‐triazoles have been regarded as highly significant nitrogen‐containing
heterocycles due to their broad spectrum of biological activities and other prominent …

The combination of CuI and glycerol exhibits a versatile and high catalytic activity in the
Huisgen cycloaddition of azides and terminal or 1-iodoalkynes under standard bench …

Abstract Six novel ciprofloxacin-1, 2, 3-triazole hybrids (6a-f) were synthesized via click
reaction, by reacting of methyl 1-cyclopropyl-6-fluoro-4-oxo-7-(4-(3-oxobutanoyl) piperazin-1 …

Huisgen cycloaddition reaction has been originally utilized for the synthesis of 1, 2, 3-
triazoles regioisomers. In this review, its stereochemistry and also mechanistical features of …

We report the synthesis of 1, 4-diaryl-5-cyano-1, 2, 3-triazoles from azides and alkynes via
two copper-mediated steps. Aryl-substituted cyanotriazoles are emissive in nonpolar …

5-Iodo-1, 2, 3-triazole (iodotriazole) can be prepared from a copper (I)-catalyzed reaction
between azide and terminal alkyne in the presence of an iodinating agent, with 5-protio-1, 2 …