Transforming growth factor-β1 (TGF-β) was first implicated in mammary epithelial
development by Daniel and Silberstein in 1987 and in breast cancer cells and hormone …

The triage theory posits that some functions of micronutrients (the≈ 40 essential vitamins,
minerals, fatty acids, and amino acids) are restricted during shortage and that functions …

Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …

Motivation To curate and organize expensive spaceflight experiments conducted aboard
space stations and maximize the scientific return of investment, while democratizing access …

Exposure to ionising radiation results in mutagenesis and cell death, and the clinical
manifestations depend on the dose and the involved body area. Reducing carcinogenesis in …

In preparation for lunar and Mars missions it is essential to consider the challenges to
human health that are posed by long-duration deep space habitation via multiple stressors …

Abstract Knowledge about established breast carcinogens can support improved and
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …

TGFβ signaling and the DNA damage response (DDR) are two cellular toolboxes with a
strong impact on cancer biology. While TGFβ as a pleiotropic cytokine affects essentially all …

Ionizing radiation is a pillar of cancer therapy that is deployed in more than half of all
malignancies. The therapeutic effect of radiation is attributed to induction of DNA damage …

Radiation-induced foci (RIF) are nuclear puncta visualized by immunostaining of proteins
that regulate DNA double-strand break (DSB) repair after exposure to ionizing radiation. RIF …