Anti-inflammatory activity of extracts and pure compounds derived from plants via modulation of signaling pathways, especially PI3K/AKT in macrophages

A Merecz-Sadowska, P Sitarek, T Śliwiński… - International journal of …, 2020 - mdpi.com
The plant kingdom is a source of important therapeutic agents. Therefore, in this review, we
focus on natural compounds that exhibit efficient anti-inflammatory activity via modulation …

[HTML][HTML] The effects and mechanisms of the anti-COVID-19 traditional Chinese medicine, Dehydroandrographolide from Andrographis paniculata (Burm. f.) Wall, on …

Z Pu, B Sui, X Wang, W Wang, L Li, H Xie - Phytomedicine, 2023 - Elsevier
Abstract Background Dehydroandrographolide (Deh) from Andrographis paniculata (Burm.
f.) Wall has strong anti-inflammatory and antioxidant activities. Purpose To explore the role …

Genome and metabolites analysis reveal insights into control of foodborne pathogens in fresh-cut fruits by Lactobacillus pentosus MS031 isolated from Chinese …

L Yi, T Qi, J Ma, K Zeng - Postharvest Biology and Technology, 2020 - Elsevier
The presence of pathogens in fresh-cut fruits represents a risk for the public health since
these products generally do not receive any further treatment before consumption. In this …

Therapeutic potential of selected medicinal plants against carrageenan induced inflammation in rats

H Fatima, M Shahid, A Jamil, M Naveed - Dose-Response, 2021 - journals.sagepub.com
The current study was aimed to analyze the therapeutic effect of selected medicinal plants,
that is, Curcuma longa, Zingiber officinale, Trigonella graceum-foenum, Nigella sativa, and …

[HTML][HTML] Knockdown of phosphoinositide-dependent kinase 1 (PDK1) inhibits fibrosis and inflammation in lipopolysaccharide-induced acute lung injury rat model by …

K Yang, B Li, J Chen - Annals of translational medicine, 2021 - ncbi.nlm.nih.gov
Background Acute lung injury (ALI) is a common inflammatory disease of the lung. This
study aimed to investigate the effect of 3-phosphoinositide-dependent kinase 1 (PDK1) …

Guettarda crispiflora Vahl Methanol Extract Ameliorates Acute Lung Injury and Gastritis by Suppressing Src Phosphorylation

D Lee, JW Kim, CY Lee, J Oh, SH Hwang, M Jo… - Plants, 2022 - mdpi.com
Many species in the genus Guettarda are known to exert anti-inflammatory effects and are
used as traditional medicinal plants to treat various inflammatory symptoms. However, no …

Anti-Gastritis and Anti-Lung Injury Effects of Pine Tree Ethanol Extract Targeting Both NF-κB and AP-1 Pathways

SA Kim, J Oh, SR Choi, CH Lee, BH Lee, MN Lee… - Molecules, 2021 - mdpi.com
An ethanol extract (Pd-EE) of Pinus densiflora Siebold and Zucc was derived from the
branches of pine trees. According to the Donguibogam, pine resin has the effects of lowering …

[HTML][HTML] Natural products that target macrophages in treating non-alcoholic steatohepatitis

CL Li, WJ Zhou, G Ji, L Zhang - World Journal of Gastroenterology, 2020 - ncbi.nlm.nih.gov
Nonalcoholic steatohepatitis (NASH) is the progressive subtype of non-alcoholic fatty liver
disease and potentiates risks for both hepatic and metabolic diseases. Although the …

Artemisia iwayomogi (Dowijigi) inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppressing the NF-κB signaling pathway

SM Kim, P Vetrivel, HH Kim, SE Ha… - Experimental and …, 2020 - spandidos-publications.com
Inflammatory diseases are an important health concern and have a growing incidence
worldwide. Thus, developing novel and safe drugs to treat these disorders remains an …

Protium javanicum Burm. Methanol Extract Attenuates LPS‐Induced Inflammatory Activities in Macrophage‐Like RAW264.7 Cells

A Ahujaa, MY Kim, JY Cho - Evidence‐Based Complementary …, 2019 - Wiley Online Library
Protium javanicum Burm. f. is a medicinal plant used in traditional medicine. Gum and
oleoresins from this plant have been used as anti‐inflammatory agents for treating ulcers …