Oxidative stress, antioxidants and hypertension

M Amponsah-Offeh, P Diaba-Nuhoho, S Speier… - Antioxidants, 2023 - mdpi.com
As a major cause of morbidity and mortality globally, hypertension remains a serious threat
to global public health. Despite the availability of many antihypertensive medications …

Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism

BA Golomb, MA Evans - American Journal of Cardiovascular Drugs, 2008 - Springer
HMG-CoA reductase inhibitors (statins) are a widely used class of drug, and like all
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …

Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure

M Aviram, L Dornfeld - Atherosclerosis, 2001 - Elsevier
Consumption of pomegranate juice which is rich in tannins, possess anti-atherosclerotic
properties which could be related to its potent anti-oxidative characteristics. As some …

Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR

X Chen, RM Touyz, JB Park, EL Schiffrin - Hypertension, 2001 - Am Heart Assoc
Ascorbic acid (vitamin C) and α-tocopherol (vitamin E) have antioxidant properties that could
improve redox-sensitive vascular changes associated with hypertension. We determined …

Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome

A Kumar, H Kaur, P Devi, V Mohan - Pharmacology & therapeutics, 2009 - Elsevier
Coenzyme Q10 (ubiquinone) is a mitochondrial coenzyme which is essential for the
production of ATP. Being at the core of cellular energy processes it assumes importance in …

Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes

JM Hodgson, GF Watts, DA Playford, V Burke… - European journal of …, 2002 - nature.com
Objective: Our objective was to assess effects of dietary supplementation with coenzyme Q
10 (CoQ) on blood pressure and glycaemic control in subjects with type 2 diabetes, and to …

Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials

FL Rosenfeldt, SJ Haas, H Krum, A Hadj, K Ng… - Journal of human …, 2007 - nature.com
Our objective was to review all published trials of coenzyme Q 10 for hypertension, assess
overall efficacy and consistency of therapeutic action and side effect incidence. Meta …

Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats

M Sánchez, M Galisteo, R Vera, IC Villar… - Journal of …, 2006 - journals.lww.com
Results In SHR, quercetin reduced the increase in blood pressure and heart rate and
enhanced the endothelium-dependent aortic vasodilation induced by acetylcholine, but had …

Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD (P) H oxidase activities

S Ülker, PP McKeown, U Bayraktutan - Hypertension, 2003 - Am Heart Assoc
Antioxidant vitamins C and E have protective properties in genetic hypertension associated
with enhanced oxidative stress. This study investigated whether vitamins C and/or E …

Nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension

MC Houston - Progress in cardiovascular diseases, 2005 - Elsevier
Vascular biology assumes a pivotal role in the initiation and perpetuation of hypertension
and target organ damage sequelae. Endothelial activation, oxidative stress, and vascular …