Cannabis sativa: The Plant of the Thousand and One Molecules

CM Andre, JF Hausman, G Guerriero - Frontiers in plant science, 2016 - frontiersin.org
Cannabis sativa L. is an important herbaceous species originating from Central Asia, which
has been used in folk medicine and as a source of textile fiber since the dawn of times. This …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Therapeutic and medicinal uses of terpenes

D Cox-Georgian, N Ramadoss, C Dona… - Medicinal plants: from …, 2019 - Springer
Terpenes, also known as terpenoids are the largest and most diverse group of naturally
occurring compounds. Based on the number of isoprene units they have, they are classified …

Are cannabidiol and Δ9‐tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

JM McPartland, M Duncan, V Di Marzo… - British journal of …, 2015 - Wiley Online Library
Based upon evidence that the therapeutic properties of C annabis preparations are not
solely dependent upon the presence of Δ9‐tetrahydrocannabinol (THC), pharmacological …

Changing landscape of cannabis: novel products, formulations, and methods of administration

TR Spindle, MO Bonn-Miller, R Vandrey - Current opinion in psychology, 2019 - Elsevier
Laws regulating cannabis have changed radically in the US and abroad. Historically, users
smoked dried cannabis flowers that contained Δ9-tetrahydrocannabinol (THC), the primary …

Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol

DL Boggs, JD Nguyen, D Morgenson… - …, 2018 - nature.com
The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its
psychotropic and mind-altering side effects for millennia. There has been growing attention …

In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

G Watt, T Karl - Frontiers in pharmacology, 2017 - frontiersin.org
Alzheimer's disease (AD) is a debilitating neurodegenerative disease that is affecting an
increasing number of people. It is characterized by the accumulation of amyloid-β and tau …

Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition

TR Arkell, N Lintzeris, RC Kevin, JG Ramaekers… - …, 2019 - Springer
Background The main psychoactive component of cannabis, delta-9-tetrahydrocannabinol
(THC), can impair driving performance. Cannabidiol (CBD), a non-intoxicating cannabis …

A systematic review of the antipsychotic properties of cannabidiol in humans

TA Iseger, MG Bossong - Schizophrenia research, 2015 - Elsevier
Despite extensive study over the past decades, available treatments for schizophrenia are
only modestly effective and cause serious metabolic and neurological side effects …

Cannabinoids and cytochrome P450 interactions

O Zendulka, G Dovrtelova, K Nosková… - Current drug …, 2016 - ingentaconnect.com
Objective: This review consists of three parts, representing three different possibilities of
interactions between cannabinoid receptor ligands of both exogenous and endogenous …