Three‑dimensional cell culture: A powerful tool in tumor research and drug discovery

D Lv, Z Hu, L Lu, H Lu, X Xu - Oncology letters, 2017 - spandidos-publications.com
In previous years, three‑dimensional (3D) cell culture technology has become a focus of
research in tumor cell biology, using a variety of methods and materials to mimic the in vivo …

Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices

RR Sharma, K Pollock, A Hubel, D McKenna - Transfusion, 2014 - Wiley Online Library
Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …

Adipose‐derived stem cell: a better stem cell than BMSC

Y Zhu, T Liu, K Song, X Fan, X Ma… - Cell Biochemistry and …, 2008 - Wiley Online Library
To further study the proliferation and multi-differentiation potentials of adipose-derived stem
cells (ADSCs), the cells were isolated with improved methods and their growth curves were …

Bone tissue engineering bioreactors: dynamic culture and the influence of shear stress

AB Yeatts, JP Fisher - Bone, 2011 - Elsevier
A bone tissue engineering strategy involving the in vitro expansion of cells on a scaffold
before implantation into the body represents a promising alternative to current clinical …

The mechanical environment of bone marrow: a review

UA Gurkan, O Akkus - Annals of biomedical engineering, 2008 - Springer
Bone marrow is a viscous tissue that resides in the confines of bones and houses the vitally
important pluripotent stem cells. Due to its confinement by bones, the marrow has a unique …

Overview of current adipose-derived stem cell (ADSCs) processing involved in therapeutic advancements: flow chart and regulation updates before and after COVID …

L Mazini, M Ezzoubi, G Malka - Stem cell research & therapy, 2021 - Springer
Adipose-derived stem cells (ADSCs) have raised big interest in therapeutic applications in
regenerative medicine and appear to fulfill the criteria for a successful cell therapy. Their low …

Toward a clinical-grade expansion of mesenchymal stem cells from human sources: a microcarrier-based culture system under xeno-free conditions

F Santos, PZ Andrade, MM Abecasis… - … Engineering Part C …, 2011 - liebertpub.com
The immunomodulatory properties of mesenchymal stem cells (MSCs) make them attractive
therapeutic agents for a wide range of diseases. However, the highly demanding cell doses …

Stem cell cultivation in bioreactors

CAV Rodrigues, TG Fernandes, MM Diogo… - Biotechnology …, 2011 - Elsevier
Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …

Mesenchymal stem cell tissue engineering: techniques for isolation, expansion and application

I Pountos, D Corscadden, P Emery, PV Giannoudis - Injury, 2007 - Elsevier
Mesenchymal stem cells (MSCs) are undifferentiated multipotent cells which reside in
various human tissues and have the potential to differentiate into osteoblasts, chondrocytes …

Biomaterials approach to expand and direct differentiation of stem cells

C Chai, KW Leong - Molecular therapy, 2007 - cell.com
Stem cells play increasingly prominent roles in tissue engineering and regenerative
medicine. Pluripotent embryonic stem (ES) cells theoretically allow every cell type in the …