Lipid-based nanoparticles for drug/gene delivery: An overview of the production techniques and difficulties encountered in their industrial development

M Mehta, TA Bui, X Yang, Y Aksoy, EM Goldys… - ACS Materials …, 2023 - ACS Publications
Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …

A review of the structure, preparation, and application of NLCs, PNPs, and PLNs

Q Li, T Cai, Y Huang, X Xia, SPC Cole, Y Cai - Nanomaterials, 2017 - mdpi.com
Nanostructured lipid carriers (NLCs) are modified solid lipid nanoparticles (SLNs) that retain
the characteristics of the SLN, improve drug stability and loading capacity, and prevent drug …

Natamycin solid lipid nanoparticles–sustained ocular delivery system of higher corneal penetration against deep fungal keratitis: preparation and optimization

A Khames, MA Khaleel, MF El-Badawy… - International journal …, 2019 - Taylor & Francis
Background Fungal keratitis (FK) is a serious pathogenic condition usually associated with
significant ocular morbidity. Natamycin (NAT) is the first-line and only medication approved …

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges

MM Wen, NS El-Salamouni, WM El-Refaie… - Journal of controlled …, 2017 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the
rapidly growing elderly population in the developing world. The currently FDA approved …

Recent progress of solid lipid nanoparticles and nanostructured lipid carriers as ocular drug delivery platforms

V Gugleva, V Andonova - Pharmaceuticals, 2023 - mdpi.com
Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Fortification by design: A rational approach to designing vitamin D delivery systems for foods and beverages

VK Maurya, A Shakya, K Bashir, K Jan… - … Reviews in Food …, 2023 - Wiley Online Library
Over the past few decades, vitamin D deficiency has been recognized as a serious global
public health challenge. The World Health Organization has recommended fortification of …

Application of lipid nanoparticles to ocular drug delivery

L Battaglia, L Serpe, F Foglietta, E Muntoni… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Although eye drops are widely used as drug delivery systems for the anterior
segment of the eye, they are also associated with poor drug bioavailability due to transient …

Nanotechnology: from in vivo imaging system to controlled drug delivery

M Mir, S Ishtiaq, S Rabia, M Khatoon, A Zeb… - Nanoscale research …, 2017 - Springer
Science and technology have always been the vitals of human's struggle, utilized
exclusively for the development of novel tools and products, ranging from micro-to nanosize …

Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders

S Md, SK Bhattmisra, F Zeeshan, N Shahzad… - Journal of Drug Delivery …, 2018 - Elsevier
A major hurdle for the treatment of neurodegenerative disorders is the inability of drug
molecules to cross the blood-brain barrier (BBB). Many anti-Parkinson and anti-Alzheimer …

Different nanotechnology approaches for ciprofloxacin delivery against multidrug-resistant microbes

AT Yayehrad, GB Wondie, T Marew - Infection and drug resistance, 2022 - Taylor & Francis
The percentages of organisms exhibiting antimicrobial resistance, especially resistance to
multiple antibiotics, are incessantly increasing. Studies investigated that many bacteria are …