[HTML][HTML] The etiology of rheumatoid arthritis

HU Scherer, T Häupl, GR Burmester - Journal of autoimmunity, 2020 - Elsevier
Rheumatoid arthritis is a heterogeneous disease, which can be, based on data combining
genetic risk factors and autoantibodies, sub-classified into ACPA-positive and-negative RA …

Persistent inflammatory and non-inflammatory mechanisms in refractory rheumatoid arthritis

MH Buch, S Eyre, D McGonagle - Nature Reviews Rheumatology, 2021 - nature.com
Despite nearly three decades of advances in the management of rheumatoid arthritis (RA), a
substantial minority of patients are exposed to multiple DMARDs without necessarily …

[HTML][HTML] An overview of autoantibodies in rheumatoid arthritis

MAM van Delft, TWJ Huizinga - Journal of autoimmunity, 2020 - Elsevier
Rheumatoid arthritis (RA) is a systemic auto-immune disease principally effecting synovial
joints. RA is characterized by immune cell infiltration in the joint. The presence of …

Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis

D van der Woude, AHM van der Helm-van - Best practice & research …, 2018 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation,
which affects approximately 1% of the population. The benefit of early recognition and …

Etiology and risk factors for rheumatoid arthritis: a state-of-the-art review

VC Romão, JE Fonseca - Frontiers in medicine, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is the most common systemic inflammatory rheumatic disease. It is
associated with significant burden at the patient and societal level. Extensive efforts have …

The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting

V Malmström, AI Catrina, L Klareskog - Nature Reviews Immunology, 2017 - nature.com
Patients with rheumatoid arthritis can be divided into two major subsets characterized by the
presence versus absence of antibodies to citrullinated protein antigens (ACPAs) and of …

The role of autoantibodies in the pathophysiology of rheumatoid arthritis

V Derksen, TWJ Huizinga… - Seminars in …, 2017 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation.
The presence of autoantibodies in the sera of RA patients has provided many clues to the …

The pathogenesis of rheumatoid arthritis

IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
The Pathogenesis of Rheumatoid Arthritis | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

The pre-clinical phase of rheumatoid arthritis: from risk factors to prevention of arthritis

N Petrovská, K Prajzlerová, J Vencovský, L Šenolt… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …

2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

D Aletaha, T Neogi, AJ Silman, J Funovits… - Arthritis & …, 2010 - Wiley Online Library
Abstract Objective The 1987 American College of Rheumatology (ACR; formerly, the
American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have …