Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers

CH Lin, CH Chen, ZC Lin, JY Fang - Journal of food and drug analysis, 2017 - Elsevier
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …

Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: Current evidence from in vitro and in vivo evaluation

S Doktorovova, AB Kovačević, ML Garcia… - European Journal of …, 2016 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were designed as
exceptionally safe colloidal carriers for the delivery of poorly soluble drugs. SLN/NLC have …

Epigenetics in cancer therapy and nanomedicine

A Roberti, AF Valdes, R Torrecillas, MF Fraga… - Clinical …, 2019 - Springer
The emergence of nanotechnology applied to medicine has revolutionized the treatment of
human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs …

Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Engineering nano‐and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport

YB Miao, YJ Lin, KH Chen, PK Luo… - Advanced …, 2021 - Wiley Online Library
Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages
of protecting against hepatic first‐pass metabolism of the drug and improving its …

Solid lipid nanoparticles and nanostructured lipid carriers in oral cancer drug delivery

S Nasirizadeh, B Malaekeh-Nikouei - Journal of Drug Delivery Science and …, 2020 - Elsevier
Most cancer disease can be treated by the parenteral anticancer delivery method. The
intravenous route takes the wholly bioavailable, accurate dose of the drug immediately to …

Development of a graphene oxide nanocarrier for dual-drug chemo-phototherapy to overcome drug resistance in cancer

TH Tran, HT Nguyen, TT Pham, JY Choi… - … applied materials & …, 2015 - ACS Publications
Despite tremendous progress in chemotherapy, drug resistance remains a major challenge
for anticancer treatment. The combinations of chemo-photothermal and chemo-chemo …

Recent advances in nanotheranostics for triple negative breast cancer treatment

V Thakur, RV Kutty - Journal of Experimental & Clinical Cancer Research, 2019 - Springer
Triple-negative breast cancer (TNBC) is the most complex and aggressive type of breast
cancer encountered world widely in women. Absence of hormonal receptors on breast …

Hyaluronic acid-coated solid lipid nanoparticles for targeted delivery of vorinostat to CD44 overexpressing cancer cells

TH Tran, JY Choi, T Ramasamy, DH Truong… - Carbohydrate …, 2014 - Elsevier
Hyaluronic acid (HA)-decorated solid lipid nanoparticles (SLNs) were developed for tumor-
targeted delivery of vorinostat (VRS), a histone deacetylase inhibitor. HA, a naturally …