Organoids are simple tissue-engineered cell-based in vitro models that recapitulate many
aspects of the complex structure and function of the corresponding in vivo tissue. They can …

Biomimetic materials have emerged as attractive and competitive alternatives for tissue
engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or …

Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

Proper immune responses are critical for successful biomaterial implantation. Here, four
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …

Biomaterials-based biofabrication methods have gained much attention in recent years.
Among them, 3D cell printing is a pioneering technology to facilitate the recapitulation of …

Natural bone is a mineralized biological material, which serves a supportive and protective
framework for the body, stores minerals for metabolism, and produces blood cells nourishing …

Polyetheretherketone (PEEK) has gradually become the mainstream material for preparing
orthopedic implants due to its similar elastic modulus to human bone, high strength …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Abstract 3D printing offers enormous flexibility in fabrication of polymer objects with complex
geometries. However, it is not suitable for fabricating large polymer structures with …