Current and promising applications of Hf (IV)-based MOFs in clinical cancer therapy

X Chen, M Li, M Lin, C Lu, A Kumar, Y Pan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer is one of the greatest challenges in medical science today as it poses a serious
threat to human life. In view of this, myriad of therapeutic strategies are being developed for …

Application of radiosensitizers in cancer radiotherapy

L Gong, Y Zhang, C Liu, M Zhang… - International journal of …, 2021 - Taylor & Francis
Radiotherapy (RT) is a cancer treatment that uses high doses of radiation to kill cancer cells
and shrink tumors. Although great success has been achieved on radiotherapy, there is still …

Nanoscale metal− organic frameworks for combined photodynamic & radiation therapy in cancer treatment

J Liu, Y Yang, W Zhu, X Yi, Z Dong, X Xu, M Chen… - Biomaterials, 2016 - Elsevier
Nanoscale metal organic frameworks (NMOFs) have shown great potential in biomedicine
owing to their structural/chemical diversities, high molecular loading capacities, and intrinsic …

[HTML][HTML] Metal-based nanoenhancers for future radiotherapy: radiosensitizing and synergistic effects on tumor cells

Y Liu, P Zhang, F Li, X Jin, J Li, W Chen, Q Li - Theranostics, 2018 - ncbi.nlm.nih.gov
Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past
decade, there has been growing interest in using high Z (atomic number) elements …

Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications

K Zarschler, L Rocks, N Licciardello, L Boselli… - … , Biology and Medicine, 2016 - Elsevier
Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …

Stimuli-responsive small-on-large nanoradiosensitizer for enhanced tumor penetration and radiotherapy sensitization

W Fu, X Zhang, L Mei, R Zhou, W Yin, Q Wang, Z Gu… - ACS …, 2020 - ACS Publications
Development of an efficient nanoradiosensitization system that enhances the radiation
doses in cancer cells to sensitize radiotherapy (RT) while sparing normal tissues is highly …

Harnessing Hafnium‐Based Nanomaterials for Cancer Diagnosis and Therapy

S Ding, L Chen, J Liao, Q Huo, Q Wang, G Tian, W Yin - Small, 2023 - Wiley Online Library
With the rapid development of nanotechnology and nanomedicine, there are great interests
in employing nanomaterials to improve the efficiency of disease diagnosis and treatment …

Sequentially triggered delivery system of black phosphorus quantum dots with surface charge-switching ability for precise tumor radiosensitization

L Chan, P Gao, W Zhou, C Mei, Y Huang, XF Yu… - ACS …, 2018 - ACS Publications
Cancer radiotherapy suffers from drawbacks such as radiation resistance of hypoxic cells,
excessive radiation that causes damage of adjacent healthy tissues, and concomitant side …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

A novel approach to low-temperature synthesis of cubic HfO2 nanostructures and their cytotoxicity

N Kumar, BPA George, H Abrahamse, V Parashar… - Scientific reports, 2017 - nature.com
The development of a strategy to stabilise the cubic phase of HfO2 at lower temperatures is
necessary for the emergence of unique properties that are not realised in the …