Abstract Ischemia/reperfusion (I/R) of the heart leads to increased autophagic flux.
Preconditioning stimulates autophagic flux by AMPK and PI3-kinase activation and mTOR …

This is a collaboration between the British Society of Gastroenterology (BSG) and the
European Society of Gastrointestinal Endoscopy (ESGE), and is a scheduled update of their …

It has been documented that Ca 2+ overload and increased production of reactive oxygen
species play a significant role in reperfusion injury (RI) of cardiomyocytes …

Background: The efficacy and safety of a reduced dose of prasugrel versus a standard dose
of ticagrelor in elderly patients or those with a low body weight presenting with an acute …

Background: Data on the comparative efficacy and safety of ticagrelor versus prasugrel in
patients with ST-segment–elevation myocardial infarction undergoing primary percutaneous …

Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is essential after
percutaneous coronary intervention (PCI), while many studies have focused on determining …

Background Female patients have been shown to experience worse clinical outcomes after
acute myocardial infarction (AMI) compared with male patients. However, it is unclear what …

Background The use of percutaneous coronary intervention (PCI) in patients with ST‐
segment elevation myocardial infarction (STEMI) is associated with a mortality rate of 5 …

Background Ticagrelor reduces ischaemic end points in acute coronary syndromes.
However, outcomes of ticagrelor versus clopidogrel in real‐world patients with acute …

Abstract The British Cardiovascular Intervention Society (BCIS) percutaneous coronary
intervention (PCI) registry is hosted by the National Institute of Cardiovascular Outcomes …