Neurofluids and the glymphatic system: anatomy, physiology, and imaging

DJJ Wang, J Hua, D Cao, ML Ho - The British journal of …, 2023 - academic.oup.com
First described in 2012, the glymphatic system is responsible for maintaining homeostasis
within the central nervous system, including nutrient delivery, waste clearance, and …

Automated generation of 0D and 1D reduced‐order models of patient‐specific blood flow

MR Pfaller, J Pham, A Verma, L Pegolotti… - … journal for numerical …, 2022 - Wiley Online Library
Abstract Three‐dimensional (3D) cardiovascular fluid dynamics simulations typically require
hours to days of computing time on a high‐performance computing cluster. One …

Review of in silico models of cerebral blood flow in health and pathology

S Payne, TI Józsa, WK El-Bouri - Progress in Biomedical …, 2023 - iopscience.iop.org
In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …

Real-time phase-contrast MRI to monitor cervical blood and cerebrospinal fluid flow beat-by-beat variability

G Baselli, F Fasani, L Pelizzari, M Cazzoli, F Baglio… - Biosensors, 2022 - mdpi.com
Beat-by-beat variability (BBV) rhythms are observed in both cardiovascular (CV) and
intracranial (IC) compartments, yet interactions between the two are not fully understood …

Effect of intracranial pressure on photoplethysmographic waveform in different cerebral perfusion territories: A computational study

H Liu, F Pan, X Lei, J Hui, R Gong, J Feng… - Frontiers in …, 2023 - frontiersin.org
Background: Intracranial photoplethysmography (PPG) signals can be measured from
extracranial sites using wearable sensors and may enable long-term non-invasive …

[HTML][HTML] High-order fully well-balanced numerical methods for one-dimensional blood flow with discontinuous properties

E Pimentel-García, LO Müller, EF Toro… - Journal of Computational …, 2023 - Elsevier
In this paper, we are interested in the numerical study of the one-dimensional blood flow
model with discontinuous mechanical and geometrical properties. We present the …

An anatomically detailed arterial-venous network model. Cerebral and coronary circulation

LO Müller, SM Watanabe, EF Toro, RA Feijóo… - Frontiers in …, 2023 - frontiersin.org
In recent years, several works have addressed the problem of modeling blood flow
phenomena in veins, as a response to increasing interest in modeling pathological …

Modeling essential hypertension with a closed‐loop mathematical model for the entire human circulation

M Celant, EF Toro, G Bertaglia, S Cozzio… - International Journal …, 2023 - Wiley Online Library
Arterial hypertension, defined as an increase in systemic arterial pressure, is a major risk
factor for the development of diseases affecting the cardiovascular system. Every year, 9.4 …

Vascular synthesis based on hemodynamic efficiency principle recapitulates measured cerebral circulation properties in the human brain

AA Linninger, T Ventimiglia… - Journal of Cerebral …, 2024 - journals.sagepub.com
Quantifying anatomical and hemodynamical properties of the brain vasculature in vivo is
difficult due to limited spatiotemporal resolution neuroimaging, variability between subjects …

Numerical coupling of 0D and 1D models in networks of vessels including transonic flow conditions. Application to short‐term transient and stationary hemodynamic …

J Murillo, P García‐Navarro - International Journal for …, 2023 - Wiley Online Library
When modeling complex fluid networks using one‐dimensional (1D) approaches, boundary
conditions can be imposed using zero‐dimensional (0D) models. An application case is the …