Sarcopenia: aging-related loss of muscle mass and function
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …
diminishes quality of life, and can lead to fall-related injuries, which require costly …
The origin and diversification of mitochondria
Mitochondria are best known for their role in the generation of ATP by aerobic respiration.
Yet, research in the past half century has shown that they perform a much larger suite of …
Yet, research in the past half century has shown that they perform a much larger suite of …
MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
The mammalian mitochondrial proteome is under dual genomic control, with 99% of proteins
encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA) …
encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA) …
[HTML][HTML] Algae–bacteria interactions: evolution, ecology and emerging applications
Algae and bacteria have coexisted ever since the early stages of evolution. This coevolution
has revolutionized life on earth in many aspects. Algae and bacteria together influence …
has revolutionized life on earth in many aspects. Algae and bacteria together influence …
MitoCarta2. 0: an updated inventory of mammalian mitochondrial proteins
Mitochondria are complex organelles that house essential pathways involved in energy
metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial …
metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial …
Deep mitochondrial origin outside the sampled alphaproteobacteria
Mitochondria are ATP-generating organelles, the endosymbiotic origin of which was a key
event in the evolution of eukaryotic cells. Despite strong phylogenetic evidence that …
event in the evolution of eukaryotic cells. Despite strong phylogenetic evidence that …
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation
LH Boudreau, AC Duchez, N Cloutier… - Blood, The Journal …, 2014 - ashpublications.org
Mitochondrial DNA (mtDNA) is a highly potent inflammatory trigger and is reportedly found
outside the cells in blood in various pathologies. Platelets are abundant in blood where they …
outside the cells in blood in various pathologies. Platelets are abundant in blood where they …
Cells within cells: Rickettsiales and the obligate intracellular bacterial lifestyle
J Salje - Nature Reviews Microbiology, 2021 - nature.com
The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …
that include many organisms of clinical and agricultural importance, including Anaplasma …
Microbial genetic composition tunes host longevity
B Han, P Sivaramakrishnan, CCJ Lin, IAA Neve, J He… - Cell, 2017 - cell.com
Homeostasis of the gut microbiota critically influences host health and aging. Developing
genetically engineered probiotics holds great promise as a new therapeutic paradigm to …
genetically engineered probiotics holds great promise as a new therapeutic paradigm to …
The crosstalk between the gut microbiota and mitochondria during exercise
Many physiological changes occur in response to endurance exercise in order to adapt to
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …