Sarcopenia: aging-related loss of muscle mass and function

L Larsson, H Degens, M Li, L Salviati… - Physiological …, 2019 - journals.physiology.org
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

The origin and diversification of mitochondria

AJ Roger, SA Muñoz-Gómez, R Kamikawa - Current Biology, 2017 - cell.com
Mitochondria are best known for their role in the generation of ATP by aerobic respiration.
Yet, research in the past half century has shown that they perform a much larger suite of …

MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

S Rath, R Sharma, R Gupta, T Ast, C Chan… - Nucleic acids …, 2021 - academic.oup.com
The mammalian mitochondrial proteome is under dual genomic control, with 99% of proteins
encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA) …

[HTML][HTML] Algae–bacteria interactions: evolution, ecology and emerging applications

R Ramanan, BH Kim, DH Cho, HM Oh, HS Kim - Biotechnology advances, 2016 - Elsevier
Algae and bacteria have coexisted ever since the early stages of evolution. This coevolution
has revolutionized life on earth in many aspects. Algae and bacteria together influence …

MitoCarta2. 0: an updated inventory of mammalian mitochondrial proteins

SE Calvo, KR Clauser, VK Mootha - Nucleic acids research, 2016 - academic.oup.com
Mitochondria are complex organelles that house essential pathways involved in energy
metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial …

Deep mitochondrial origin outside the sampled alphaproteobacteria

J Martijn, J Vosseberg, L Guy, P Offre, TJG Ettema - Nature, 2018 - nature.com
Mitochondria are ATP-generating organelles, the endosymbiotic origin of which was a key
event in the evolution of eukaryotic cells. Despite strong phylogenetic evidence that …

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

LH Boudreau, AC Duchez, N Cloutier… - Blood, The Journal …, 2014 - ashpublications.org
Mitochondrial DNA (mtDNA) is a highly potent inflammatory trigger and is reportedly found
outside the cells in blood in various pathologies. Platelets are abundant in blood where they …

Cells within cells: Rickettsiales and the obligate intracellular bacterial lifestyle

J Salje - Nature Reviews Microbiology, 2021 - nature.com
The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

Microbial genetic composition tunes host longevity

B Han, P Sivaramakrishnan, CCJ Lin, IAA Neve, J He… - Cell, 2017 - cell.com
Homeostasis of the gut microbiota critically influences host health and aging. Developing
genetically engineered probiotics holds great promise as a new therapeutic paradigm to …

The crosstalk between the gut microbiota and mitochondria during exercise

A Clark, N Mach - Frontiers in physiology, 2017 - frontiersin.org
Many physiological changes occur in response to endurance exercise in order to adapt to
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …