Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

Brain organoids are self-assembled three-dimensional aggregates generated from
pluripotent stem cells with cell types and cytoarchitectures that resemble the embryonic …

Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

The mammalian brain is composed of an outer layer of gray matter, consisting of cell bodies,
dendrites, and unmyelinated axons, and an inner core of white matter, consisting primarily of …

The rapid growth of the human cortex during development is accompanied by the folding of
the brain into a highly convoluted structure,,. Recent studies have focused on the genetic …

The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

Neurodevelopment is a complex, dynamic process that involves a precisely orchestrated
sequence of genetic, environmental, biochemical, and physical events. Developmental …

Brain stiffness plays an important role in neuronal development and disease, but reported
stiffness values vary significantly for different species, for different brains, and even for …

One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …