The cytoskeleton—a complex interacting meshwork

T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Post-translational modifications of intermediate filament proteins: mechanisms and functions

NT Snider, MB Omary - Nature reviews Molecular cell biology, 2014 - nature.com
Intermediate filaments (IFs) are cytoskeletal and nucleoskeletal structures that provide
mechanical and stress-coping resilience to cells, contribute to subcellular and tissue-specific …

Vimentin intermediate filaments and filamentous actin form unexpected interpenetrating networks that redefine the cell cortex

H Wu, Y Shen, S Sivagurunathan… - Proceedings of the …, 2022 - National Acad Sciences
The cytoskeleton of eukaryotic cells is primarily composed of networks of filamentous
proteins, F-actin, microtubules, and intermediate filaments. Interactions among the …

Intermediate filaments at the junction of mechanotransduction, migration, and development

R Sanghvi-Shah, GF Weber - Frontiers in cell and developmental …, 2017 - frontiersin.org
Mechanically induced signal transduction has an essential role in development. Cells
actively transduce and respond to mechanical signals and their internal architecture must …

Cytoskeletal control of early mammalian development

HYG Lim, N Plachta - Nature Reviews Molecular Cell Biology, 2021 - nature.com
The cytoskeleton—comprising actin filaments, microtubules and intermediate filaments—
serves instructive roles in regulating cell function and behaviour during development …

[HTML][HTML] Bidirectional interplay between vimentin intermediate filaments and contractile actin stress fibers

Y Jiu, J Lehtimäki, S Tojkander, F Cheng, H Jäälinoja… - Cell reports, 2015 - cell.com
The actin cytoskeleton and cytoplasmic intermediate filaments contribute to cell migration
and morphogenesis, but the interplay between these two central cytoskeletal elements has …

The laminin–keratin link shields the nucleus from mechanical deformation and signalling

Z Kechagia, P Sáez, M Gómez-González, B Canales… - Nature materials, 2023 - nature.com
The mechanical properties of the extracellular matrix dictate tissue behaviour. In epithelial
tissues, laminin is a very abundant extracellular matrix component and a key supporting …

Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia

R Windoffer, M Beil, TM Magin, RE Leube - Journal of Cell Biology, 2011 - rupress.org
Epithelia are exposed to multiple forms of stress. Keratin intermediate filaments are
abundant in epithelia and form cytoskeletal networks that contribute to cell type–specific …

Encapsulation of the cytoskeleton: towards mimicking the mechanics of a cell

Y Bashirzadeh, AP Liu - Soft Matter, 2019 - pubs.rsc.org
The cytoskeleton of a cell controls all the aspects of cell shape changes and motility from its
physiological functions for survival to reproduction to death. The structure and dynamics of …

Regulation of microtubule-associated motors drives intermediate filament network polarization

C Leduc, S Etienne-Manneville - Journal of Cell Biology, 2017 - rupress.org
Intermediate filaments (IFs) are key players in the control of cell morphology and structure as
well as in active processes such as cell polarization, migration, and mechanoresponses …